grant

Peptidergic neuromodulation of microcircuits that control chemosensation-induced behaviors

Organization SALK INSTITUTE FOR BIOLOGICAL STUDIESLocation La Jolla, UNITED STATESPosted 1 Apr 2017Deadline 29 Feb 2028
NIHUS FederalResearch GrantFY2025AddressAfferent NeuronsAggressionAggressive behaviorAnimal FeedAnimalsAnxietyAreaBehaviorBehavioralBehavioral ParadigmBiologicalBrainBrain Nervous SystemCNS Nervous SystemCell BodyCell Communication and SignalingCell SignalingCellsCentral Nervous SystemChemicalsCognitiveCommunicationComplexCuesDetectionDrosophilaDrosophila genusDrosophila melanogasterEncephalonEndocrine Gland SecretionEsthesiaEventExhibitsExperimental GeneticsFliesFoodFundingGeneHomologGenesGeneticGoalsGustationHomologHomologous GeneHomologueHormonesHumanHungerIndividualIntracellular Communication and SignalingKnowledgeMediatingMidgutModelingModern ManMolecularMotivationNIDCDNational Institute on Deafness and Other Communication DisordersNerve CellsNerve UnitNervous SystemNeural CellNeuraxisNeurocyteNeurohormonesNeurologic Body SystemNeurologic Organ SystemNeuromedin UNeuromedin U-25NeuromodulatorNeuronsNeuropeptidesNutrientNutritionalOdorsOlfactionOlfactory PathwaysOlfactory systemOrganism-Level ProcessOrganismal ProcessPathway interactionsPerceptionPheromonePhysiologicPhysiologic ProcessesPhysiologicalPhysiological ProcessesPhysiologyPlayPopulationProcessProteinsReceptor GeneReceptor ProteinResearchResearch ResourcesResourcesRoleSensationSensorySensory NeuronsShapesSignal TransductionSignal Transduction SystemsSignalingSmellSmell PerceptionSocial BehaviorSocial InteractionSourceSpecific qualifier valueSpecifiedStimulusStrategic PlanningTasteTaste PerceptionTestingTherapeutic HormoneTransmissionVolatilizationYeastsanimal foodbehavior responsebehavioral responsebiologicbiological signal transductionbrain celldeprivationexperimentexperimental researchexperimental studyexperimentsflyfocus on malefocused on menfruit flygustatory perceptiongustatory processinggustatory responsemale focusedmale specificmale targetedmodel organismneuralneural controlneural regulationneuromodulationneuromodulatoryneuronalneuroregulationnovelnutritiousodor perceptionolfactory circuitryolfactory circuitsolfactory perceptionolfactory sensory neuronsolfactory thresholdpathwayperceptual stimulusphysicochemical phenomena related to the sensesprogramsreceptorreproductiveresponsesensory inputsensory stimulussensory systemsmall moleculesocial rolesociobehaviorsociobehavioraltargeted to mentaste processingtaste responsetransmission process
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PROJECT SUMMARY
One of central functions of neuromodulation is to adjust the internal representations of sensory information ac-

cording to the internal states of an individual. In particular, chemosensation can have dramatically different bio-

logical meanings depending on the nutritional state. For instance, the smell of food not only informs an…

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