grant
PATIENT-TAILORED PHYSICAL ACTIVITY INTERVENTION AMONG OLDER WOMEN WITH GYNECOLOGIC CANCERS UNDERGOING CHEMOTHERAPY (FIT4TREATMENT)
Organization NORTHWESTERN UNIVERSITYLocation CHICAGO, UNITED STATESPosted 1 May 2023Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY2026AccelerometerActive Follow-upAddressAdherenceAdjuvant ChemotherapyAdjuvant Drug TherapyAgeAgingAnxietyCancer PatientCancer SurvivorCancer TreatmentCancersCaringClinical TrialsClinical Trials DesignDisseminated Malignant NeoplasmDoseExerciseFatigueFemale Reproductive CancerGoalsGynecologic CancerGynecological CancerHealthHealth BenefitHealth Care TechnologyHealth Care VisitHealth TechnologyHealth systemHistologyImpairmentIndividualInferiorInterventionKnowledgeLack of EnergyMalignant Female Reproductive System NeoplasmMalignant Gynecologic NeoplasmMalignant Gynecologic TumorMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMalignant Tumor of the Female Reproductive SystemMeasuresMediatorMetastatic CancerMetastatic Malignant NeoplasmOncologyOncology CancerOutcomeOvarianParticipantPatient Outcomes AssessmentsPatient Reported MeasuresPatient Reported OutcomesPatientsPerformancePersonsPhysical FunctionPhysical activityPopulationPopulation HeterogeneityProgression-Free SurvivalsProviderQOLQOL improvementQuality of lifeRandomization trialRandomizedRecommendationResearchResearch DesignSelf EfficacySocial supportStrenuous ExerciseStudy TypeSurvivorsSymptom BurdenSymptomsTestingTimeToxic effectToxicitiesToxicity due to chemotherapyTreatment-related toxicityUnited StatesWomanWorkaccelerated agingaccelerated biological ageaccelerated biological agingaccelerometryactive followupactivity monitoractivity trackerage accelerationage associated effectsage effectage related effectsagesaging associated diseaseaging associated disordersaging delayaging effectaging related diseaseaging related disordersanti-cancer therapyattenuate agingcancer survivalcancer therapycancer typecancer-directed therapycardiorespiratory fitnesscardiorespiratory healthcare partnercaregiving partnercervical and uterine cancerchemotherapychemotherapy toxicitydecelerate agingdecline in functiondecline in functional statusdelay age relateddelivered remotelydesigndesigningdisease associated with agingdisease of agingdisorder of agingdisorders associated with agingdisorders related to agingdiverse populationselderly patientevidence baseexercise interventionexperiencefollow upfollow-upfollowed upfollowupfrailtyfunctional declinefunctional outcomesfunctional status declinegynecologic malignancygynecological malignancyhealth related quality of lifeheterogeneous populationhigh risk grouphigh risk individualhigh risk peoplehigh risk populationimpact of ageimprovedimprovements in QOLimprovements in quality of lifeinfluence of ageinnovateinnovationinnovativeintense exercisem-HealthmHealthmalignancymobile healthmortalitymulti-component interventionmulti-faceted interventionmulti-modal interventionmulticomponent interventionmultifaceted interventionmultimodal interventionmultiphase optimization strategyneoplasm/cancerolder adultolder adulthoodolder patientolder womenpause agingphysical activity interventionpopulation diversitypostpone age relatedquality of life improvementrandomisationrandomizationrandomized trialrandomly assignedremote deliveryretards agingsarcopeniasarcopenicsedentaryslow agingslow down agingslow the rate of agingsocial support networkstrenuous activitystrenuous physical activitystudy designsuccesstherapeutic toxicitytherapy associated toxicitytherapy related toxicitytherapy toxicitytreatment toxicitytreatment-associated toxicityuterine and cervical cancervigorous exercisevigorous physical activitywearablewearable devicewearable electronicswearable systemwearable technologywearable toolwearables
Description preview
PROJECT SUMMARY
Older patients with gynecologic cancers have increased advanced stage at presentation, more aggressive
histology and more commonly require adjuvant chemotherapy. This chemotherapy, as well as underlying cancer,
cause accelerated aging and toxicity, leaving women vulnerable to functional decline, increased frailty,
decreased health…
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