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Pathways to Hope: Pilot fMRI Study of OCPD and Suicide Risk in Trauma-Exposed Veterans
Organization PROVIDENCE VA MEDICAL CENTERLocation PROVIDENCE, UNITED STATESPosted 1 Apr 2024Deadline 31 Mar 2026 ⚠️
VANIHUS FederalResearch GrantFY2025AccelerationAddressAggressionAggressive behaviorAnankastic PersonalityAngerArmed Forces PersonnelBehaviorBrainBrain Nervous SystemCaringCell Communication and SignalingCell SignalingClinicalCognitiveCompulsive Personality DisorderDataDevelopmentDevelopment and ResearchDiagnosticDisciplineDiseaseDisorderDoctor of PhilosophyEmotionalEmpathyEncephalonEvaluationExhibitsFDA approvedFunctional MRIFunctional Magnetic Resonance ImagingGoalsImpairmentIndividualInformal Social ControlInterviewIntracellular Communication and SignalingKnowledgeLearningLinkMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMedical RehabilitationMental DepressionMental HealthMental HygieneMethodsMilitaryMilitary PersonnelModelingMonitorNMR ImagingNMR TomographyNuclear Magnetic Resonance ImagingObsessive compulsive behaviorObsessive-Compulsive PersonalityOccupationalPTSDPathologyPathway interactionsPh.D.PhDPhenotypePilot ProjectsPositionPositioning AttributePost-Traumatic NeurosesPost-Traumatic Stress DisordersPosttraumatic NeurosesPredispositionProtocolProtocols documentationPsychological HealthPsychotherapyQOLQOL improvementQuality of lifeR & DR&DRehabilitationRehabilitation therapyResearchReversal LearningSamplingSelf RegulationSignal TransductionSignal Transduction SystemsSignalingSocial FunctioningSocial supportStressSuicideSuicide attemptSuicide precautionSuicide preventionSurfaceSusceptibilityTaxesTemperamentTherapeuticTraumaTreatment EffectivenessUnderserved PopulationValidationVeteransVulnerable PopulationsZeugmatographyacceptability and feasibilityangersangrybiological signal transductionburn-outburnoutco-morbidco-morbiditycognitive neurosciencecognitive rigiditycohortcomorbiditycompassion to selfcustomized therapycustomized treatmentdepressiondesigndesigningdevelopmentaldiscountingdisease riskdisorder riskemotion regulationemotional regulationexpectationexposure to traumafMRIfatal attemptfatal suicidefeasibility testingflexibilityflexiblefunction sociallyfunctioning socialhigh riskhigh standardimprovedimprovements in QOLimprovements in quality of lifeindividualized medicineindividualized patient treatmentindividualized therapeutic strategyindividualized therapyindividualized treatmentinnovateinnovationinnovativeinstrumentintent to diemilitary populationneural controlneural correlateneural regulationneuromodulationneuromodulatoryneuroregulationnon fatal attemptnon-invasive brain stimulationnonfatal attemptobsessive compulsiveobsessive compulsive personality disorderpathwaypatient specific therapiespatient specific treatmentpersonalization of treatmentpersonalized diagnosispersonalized diagnosticspersonalized medicinepersonalized therapypersonalized treatmentpilot studypost-trauma stress disorderposttrauma stress disorderprecise diagnosticsprecision diagnosticsprecision medicineprecision-based medicineprevent suicidalityprevent suicidepsychosocialquality of life improvementrecruitreduce suicidalityreduce suicidereducing suicidalityreducing suiciderehab therapyrehabilitativerehabilitative therapyremote monitoringresearch and developmentresponseself-compassionself-forgivenessself-kindnessskill acquisitionskill developmentskillssocial attachmentsocial bondingsocial defectssocial deficitssocial disorderssocial dysfunctionsocial support networksuicidalsuicidal attemptsuicidal risksuicidalitysuicidality preventionsuicide interventionsuicide risksuicidestailored medical treatmenttailored therapytailored treatmenttherapy optimizationtraittrauma exposuretraumatic neurosistraumatic stresstreating oneself with kindnesstreatment optimizationunder served groupunder served individualunder served peopleunder served populationunderserved groupunderserved individualunderserved peopleunique treatmentvalidationsvulnerable groupvulnerable individualvulnerable people
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Project Summary/Abstract
In military culture, high standards are revered, yet negative aspects of overcontrol are often overlooked.
Overcontrol manifests as rigid behavior, cognitive inflexibility, and a strong need for perfection. It is
predominantly seen in obsessive-compulsive (OC) spectrum disorders, especially OC Personality Disorder
(OCPD).…
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