grant
Optogenetic modeling of a hallmark neurodegeneration pathology for mechanistic research and drug discovery.
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
Purpose/aims: 1. Establish neuronal models with inducible optoDPR aggregation to comprehensively characterise DPR aggregation-induced neuropathology (primary supervisor).
2. Generate in vivo (Drosophila) optoDPR models to analyse behavioural, tissue and cellular phenotypes elicited by DPR aggregation (second supervisor).
3. Develop an optoDPR…
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