grant
Opportunistic Screening for ASCVD using a Multimodal Deep Learning Risk Prediction Model
Organization MAYO CLINIC ARIZONALocation SCOTTSDALE, UNITED STATESPosted 15 Dec 2023Deadline 30 Nov 2028
NIHUS FederalResearch GrantFY202521+ years oldASCVDAddressAdipose tissueAdultAdult HumanAlgorithmsAmericanAmerican Heart AssociationApoplexyAssessment instrumentAssessment toolAtherosclerosisAtherosclerotic Cardiovascular DiseaseBMIBMI percentileBMI z-scoreBiological MarkersBlackBlack raceBody CompositionBody mass indexBrain Vascular AccidentCAT scanCT X RayCT XrayCT imagingCT scanCalciumCardiac infarctionCardiologyCardiovascularCardiovascular Body SystemCardiovascular Organ SystemCardiovascular systemCategoriesCause of DeathCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCessation of lifeChestClinicClinicalClinical DataComputed TomographyComputerized Medical RecordCoronaryDataData ElementDeathDedicationsDependenceElectronic Medical RecordEquationEthnic OriginEthnicityEventFatty TissueFutureGenderGoalsGraphHealth systemHeart VascularImageIndividualIndividuals from minorityIndividuals of minorityIschemic HeartIschemic Heart DiseaseIschemic myocardiumManualsMethodsMinority GroupsMinority PeopleMinority PopulationMinority individualModelingMorbidityMorbidity - disease rateMyocardial InfarctMyocardial InfarctionMyocardial IschemiaNatureObesityPatientsPerformancePopulationPopulation HeterogeneityPredicting RiskPreventative interventionPreventative strategyPreventative therapyPreventionPrevention strategyPreventivePreventive strategyPreventive therapyPrimary PreventionPrognostic MarkerQuetelet indexRaceRacesRecommendationReportingRiskRisk AssessmentRisk EstimateScanningScientistSemanticsSiteSkeletal MuscleSliceStrokeTechniquesTechnologyTherapeuticThoraceThoracicThoracic aortaThoraxTomodensitometryTrainingUnited StatesUniversitiesValidationVisceralVoluntary MuscleWorkX-Ray CAT ScanX-Ray Computed TomographyX-Ray Computerized TomographyXray CAT scanXray Computed TomographyXray computerized tomographyadiposeadiposityadulthoodatheromatosisatherosclerotic diseaseatherosclerotic vascular diseasebio-markersbiologic markerbiomarkerbrain attackcardiac infarctcardiac ischemiacardiovascular disease riskcardiovascular disorder riskcatscancerebral vascular accidentcerebrovascular accidentchest CTchest computed tomographycirculatory systemclinical practicecohortcollegecollegiatecomputed axial tomographycomputer tomographycomputerized axial tomographycomputerized tomographycoronary artery calciumcoronary attackcoronary calciumcoronary infarctcoronary infarctioncoronary ischemiacorpulencedeep learningdeep learning based modeldeep learning methoddeep learning modeldeep learning strategydemographicsdesigndesigningdiverse populationsexperienceexperimentexperimental researchexperimental studyexperimentsfallsforecasting riskheart attackheart infarctheart infarctionheart ischemiaheterogeneous populationimagingimaging Segmentationimaging biomarkerimaging markerimaging-based biological markerimaging-based biomarkerimaging-based markerinsurance planintervention for preventionmid lifemid-lifemiddle agemiddle agedmidlifeminority patientmortalitymulti-modalitymultidisciplinarymultimodal data fusionmultimodal fusionmultimodalitymuscle bulkmuscle formmuscle massmyocardial ischemia/hypoxiamyocardium ischemianon-contrast CTnoncontrast CTnoncontrast computed tomographynovelpatient populationpatient screeningpatients from minoritypatients of minoritypopulation diversitypredict riskpredict riskspredicted riskpredicted riskspredicting riskspredictive riskpredictive toolspredicts riskprevention interventionpreventional intervention strategypreventive interventionprognosticprognostic biomarkerprognostic indicatorprognostic performancerace biasracialracial backgroundracial biasracial originradiologistrisk predictionrisk prediction algorithmrisk prediction modelrisk prediction systemrisk prediction toolrisk predictionsrisk stratificationscreeningscreeningssocial health determinantsstratify riskstrokedstrokessubcutaneoussubdermaltoolvalidationswhite adipose tissueyellow adipose tissue
Description preview
PROJECT SUMMARY
Atherosclerotic cardiovascular disease (ASCVD), such as stroke and heart attack, is the leading cause of
morbidity and mortality globally, responsible for approximately 19 million deaths annually. Risk assessment is
the cornerstone for primary prevention of ASCVD. Pooled Cohort Equations (PCE) are currently used to guide
risk…
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