NSF-SNSF: Morphogenesis by design: an integrated mechanobiology framework for the sculpting of architected biological tissues
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Tissue morphogenesis, or the development of tissue shape, is driven by a combination of cellular forces, mechanical constraints, and changes in extracellular matrix (ECM) composition and architecture. This combination of parameters is difficult to study. It is still unknown how mechanical forces, including external forces applied to the tissue…
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