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Novel Self-closing 12F Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Transcatheter Edge-to-Edge Repair (TEER) Technique Via Femoral Vein Access.
NIHUS FederalResearch GrantFY2025AddressAffectAnatomic ModelsAnatomical ModelsAnimalsBicuspid ValveCOVID crisisCOVID epidemicCOVID pandemicCOVID-19 affectedCOVID-19 consequenceCOVID-19 crisisCOVID-19 effectCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 impactCOVID-19 impactedCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 yearsCathetersCessation of lifeClinicalClinical ResearchClinical StudyClinical Trials Data Monitoring CommitteesContracting OpportunitiesContractsDataData Monitoring CommitteesData and Safety Monitoring BoardsDeathDevelopment and ResearchDevicesDocumentationEquipment and supply inventoriesEvaluationFDA approvedFatigueFeasibility StudiesFemoral veinFreezingFundingGoalsGovernmentHeartHumanIRBIRBsIndividualInformed ConsentInstitutional Review BoardsInterventionInventoryInvestigationLack of EnergyLengthMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMarketingMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMitral IncompetenceMitral InsufficiencyMitral RegurgitationMitral ValveMitral Valve IncompetenceMitral Valve InsufficiencyMitral Valve RegurgitationModern ManMonitorNMR ImagingNMR TomographyNational Institutes of HealthNewly DiagnosedNotificationNuclear Magnetic Resonance ImagingOperative ProceduresOperative Surgical ProceduresPatientsPersonsPhasePhysiciansPopulationPreparationProceduresProcessProtocolProtocols documentationR & DR&DReportingResearch ContractsRiskSARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 pandemicSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicSafety Monitoring BoardsSample SizeSecureSeptal VeinSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 pandemicSiteSurgicalSurgical InterventionsSurgical ProcedureSystemTechniquesTechnologyTestingUnited StatesUnited States National Institutes of HealthWritingZeugmatographyco-morbidco-morbiditycohortcommercializationcommercialization readinesscomorbiditycoronavirus disease 2019 consequencecoronavirus disease 2019 crisiscoronavirus disease 2019 effectcoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 impactcoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease-19 global pandemiccoronavirus disease-19 impactcoronavirus disease-19 pandemiccostdesigndesign validationdesign verificationdesigningfrailtyhigh riskimprovedin vitro Modelin vitro testinginnovateinnovationinnovativemanufacturemeetingmeetingsnew technologynovelnovel technologiespig modelpiglet modelporcine modelpost-COVIDpost-COVID-19post-coronavirus disease 2019pre-clinicalpreclinicalpreparationsprogramsprototypepublic health relevancerepairrepairedresearch and developmentsevere acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicsurgeryswine model
Applications closed.
Description preview
Project Summary
The MEDFREE® Valve Repair System will innovatively improve upon the current market leading MitraClip
device, while leveraging and building on the proven Transcatheter Edge-to-Edge Repair technique. We aim to
address this vastly unmet percutaneous structural heart market by delivering a simpler, easier-to-use device in
a smaller 12F…
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