grant

Novel Artificial Intelligence approaches to distinguish allergenic from non-allergenic proteins

Organization UNIVERSITY OF TEXAS MED BR GALVESTONLocation GALVESTON, UNITED STATESPosted 13 Feb 2026Deadline 31 Jan 2031
NIHUS FederalResearch GrantFY20263-D3-D modeling3-D structure3-Dimensional3-dimensional structure3D3D modeling3D structureAI based modelAI language modelsAI modelAI model trainingAI systemAI technologyAI trainingAffectAffinityAgricultureAllergensAllergicAllergic DiseaseAllergic to foodAllergyAllergy to foodAllergy to peanutsAmino Acid SequenceAnaphylactic ReactionAnaphylactic ShockAnaphylaxisAnimalsAnti-Bacterial AgentsAntigenic DeterminantsAreaArtificial IntelligenceArtificial intelligence model trainingBase SequenceBenchmarkingBest Practice AnalysisBindingBinding DeterminantsBlood SerumBreathingCashewCashew nutCell BodyCellsCharacteristicsChatGPTClassificationClinical ManagementComputer ReasoningComputer softwareConnectionist ModelsConvNetCotton PlantCross ReactionsDNADataData BasesDatabasesDeoxyribonucleic AcidDeveloped CountriesDietDiseaseDisorderDocumentationEpitopesExanthemExanthemaExclusionFabaceaeFamilyFilbertsFishesFoodFood AllergyFood HypersensitivityGPT-2GPT-3GPT-4GeneHomologGossypiumGroundnut HypersensitivityGuidelinesHazelnutsHealth Care SystemsHomologHomologous GeneHomologueHumanIgEImmune mediated therapyImmunoglobulin EImmunologically Directed TherapyImmunotherapyIndividualIndustrialized CountriesIndustrialized NationsInterleukinsInvestigatorsLanguageLegumesLeguminosaeLeguminoseaeMachine IntelligenceMachine LearningMasksMediatingMethodsMilkModelingModern ManMolecularMolecular InteractionN-Glycosylation SiteNeural Network ModelsNeural Network SimulationNucleotide SequenceNutsPatientsPeanut HypersensitivityPenetrationPeptide LibraryPeptidesPerceptronsPerformancePlantsPopulationPrevalencePrimary Protein StructurePropertyProtein DatabasesProtein FamilyProteinsProteomeRashResearchResearch PersonnelResearch ResourcesResearchersResourcesRespiratory AspirationRespiratory InspirationSchoolsSerumShellfishSkin RashSlideSoftwareSource CodeSpecific qualifier valueSpecifiedStructureSystematicsTechniquesTestingTrainingTransformer language modelTreesWeightWheatWorkWorld Health Organizationallergen responseallergic reaction to peanutallergic responseallergic response to peanutallergic to peanutsallergy responseanaphylactic response to foodanaphylaxis caused by foodanaphylaxis due to foodanaphylaxis to foodanti-bacterialartificial intelligence language modelsartificial intelligence modelartificial intelligence technologyartificial intelligence trainingartificial intelligence-based modelbenchmarkclinical diagnosiscomparativeconvolutional networkconvolutional neural netsconvolutional neural networkcottoncross reactivitydata basedeep learningdeep learning based modeldeep learning methoddeep learning modeldeep learning strategydesensitizationdesigndesigningdeveloped countrydeveloped nationdeveloped nationsdietseggfeature extractionfood allergenfood allergy anaphylaxisfood anaphylactic reactionfood anaphylaxisfood associated anaphylaxisfood induced anaphylaxisfood mediated anaphylaxisfood related anaphylaxisfood triggered anaphylaxisfungusimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyimprovedinspirationlarge language modellarge scale language modelmachine based learningmachine learning based modelmachine learning modelmanufacturemassive scale language modelsnovelnucleic acid sequencepea familypeanut allergicpeanut allergypre-trained transformerpredictive toolsprogramsprotein functionprotein sequenceprotein structureprotein structuresproteins structureresponsesoythree dimensionalthree dimensional structurethree-dimensional modelingtooltransformer architecturetransformer based modeltransformer modelweb serverweb sitewebsiteweights
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ABSTRACT
Allergic diseases have increased dramatically to become the most common human disorders in developed

countries. Despite improved clinical diagnosis and management, they are the leading cause of work and school

absences. The prevalence of food allergy is rising for unclear reasons, with prevalence estimates in the

developed countries…

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