grant
NOTRE: optimizing long-acting pre-exposure prophylaxis and medications for opioid use disorder interventions in carceral settings
NIHUS FederalResearch GrantFY202521+ years oldAIDS VirusAIDS preventionAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusActive Follow-upAdherenceAdultAdult HumanAnti-HIV PositivityAssess implementationBuprenorphineClinicalCollaborationsCommon Data ElementCommunicable DiseasesCommunitiesComplexConsolidated Framework for Implementation ResearchConsolidated Framework for Implementation ScienceConsolidated Framework for Implementing ChangeContinuity of CareContinuity of Patient CareContinuum of CareCountyDataDropoutDrugsEducationEducational aspectsEligibilityEligibility DeterminationEnvironmentEpidemicEvidence based practiceFDA approvedFaceFormulationGeneral PopulationGeneral PublicGoalsHIVHIV InfectionsHIV PositiveHIV PositivityHIV PreventionHIV SeroconversionHIV SeropositivityHIV antibody positiveHIV riskHIV/AIDS preventionHTLV-III InfectionsHTLV-III SeroconversionHTLV-III SeropositivityHTLV-III-LAV InfectionsHealthHuman Immunodeficiency VirusesHuman T-Lymphotropic Virus Type III InfectionsHybridsIRBIRBsImplementation assessmentImprisonmentIndividualInfectious DiseasesInfectious DisorderInjectableInstitutional Review BoardsInterventionInterviewInvestigatorsJailLAV-HTLV-IIILymphadenopathy-Associated VirusMaintenanceMarylandMedicalMedicationOralOutcomeParticipantPersonsPharmaceutical PreparationsPhasePopulationPrEPPrevalencePrisonsProceduresProtocolProtocol ScreeningProtocols documentationPublic HealthQualitative ResearchRandomizedResearchResearch PersonnelResearchersRiskRisk BehaviorsRisky BehaviorSafetyScreening procedureServicesSiteSurvey InstrumentSurveysTimeUnderemploymentVirus-HIVVisitWashingtonWorkactive followupadherence rateadulthoodat risk behaviorbarriers to implementationbuprenorphine treatmentcommunity partnerscommunity re-entrycommunity reentrycommunity-based partnerscompare effectivenessdisease preventiondisorder preventiondrug/agenteffectiveness and implementation trialeffectiveness/implementation hybrideffectiveness/implementation hybrid trialeffectiveness/implementation trialefficacious interventionefficacy testingevaluate implementationevaluation of implementationevidence baseexperiencefacesfacialfollow upfollow-upfollowed upfollowuphealth care settingshigh risk grouphigh risk individualhigh risk peoplehigh risk populationhousing instabilityimplementation barriersimplementation challengesimplementation evaluationimplementation facilitationimplementation outcomesimprovedimproved outcomeincarceratedincarcerationinnovateinnovationinnovativeinstably housedlack of stable housingmedication for opioid use disorderopiate use disorderopioid use disorderpre-exposure prophylaxispreventpreventingprimary outcomeprospectiverandomisationrandomizationrandomly assignedrecruitscreening toolssocialstemsubstance usesubstance usingsyndemicsynergistic epidemictrial enrollmentunderemployedunstable housingunstably houseduptake
Description preview
Co-occurring substance use and HIV risk among individuals in correctional settings presents a significant public health challenge. Approximately 17% of incarcerated individuals have an opioid use disorder (OUD), and HIV prevalence is notably higher than in the general population. Evidence-based medical interventions—such as pre-exposure…
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