grant
Non-Invasive Vagus Nerve Stimulation in Subarachnoid Hemorrhage
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 1 Feb 2026Deadline 31 Jan 2031
NIHUS FederalResearch GrantFY2026AblationAcquired brain injuryAgingAneurysmAneurysmal Subarachnoid HemorrhagesAnimal ModelAnimal Models and Related StudiesAnimalsAnti-Hypertensive AgentsAnti-Hypertensive DrugsAnti-HypertensivesAnti-InflammatoriesAnti-Inflammatory AgentsAnti-epilepticAnti-inflammatoryAttentionAutoregulationBasicraniumBasis craniiBiologicalBloodBlood - brain barrier anatomyBlood NeutrophilBlood Polymorphonuclear NeutrophilBlood Reticuloendothelial SystemBlood-Brain BarrierBody TissuesBody Weight decreasedBrain InjuriesBrain VascularCell NucleusCerebral Arterial CircleCerebral IschemiaCerebrovascular CirculationCervicalCervical nervesCircle of WillisClinicalClinical EvaluationClinical TestingCranial BaseCranial Nerve XDataDiseaseDisorderDistalDoseElastasesElectrodesEmbolismEmbolusFlowmetryFoundationsFutureHemato-Encephalic BarrierHemi-MyeloperoxidaseHistologyHomeostasisHydrocephalusHydrocephalyHypertensionHypotensive AgentHypotensive DrugsInflammationInjectionsInterventionIntracranial AneurysmIntractable EpilepsyInvestigationIschemiaLaser ElectromagneticLaser RadiationLasersLength of StayLesionMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMarrow NeutrophilMediatingMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMental DepressionMicrovascular DysfunctionModelingMyeloperoxidaseNMR ImagingNMR TomographyNerveNeutrophilic GranulocyteNeutrophilic LeukocyteNicotinic Acetylcholine ReceptorsNicotinic ReceptorsNimodipineNimotopNuclear Magnetic Resonance ImagingNucleusNumber of Days in HospitalOperative ProceduresOperative Surgical ProceduresOpticsOutcomePathway interactionsPatientsPerfusionPeripheralPeroxidasesPhysiological HomeostasisPneumogastric NervePolymorphonuclear CellPolymorphonuclear LeukocytesPolymorphonuclear NeutrophilsPropertyPublishingPuncture procedurePuncturesRefractory epilepsyRestRuptureRuptured AneurysmSafetySeizuresSiteSpontaneous RuptureSubarachnoid HemorrhageSurgicalSurgical InterventionsSurgical ProcedureSystemSystemic Inflammatory Response SyndromeTechniquesTenth Cranial NerveTestingTherapeuticTherapy Clinical TrialsThrombosisThrombusTissuesTraumaVagus NerveVagus nerve structureVascular Hypertensive DiseaseVascular Hypertensive DisorderVasospasmWeight LossWeight ReductionZeugmatographyalpha-bungarotoxin binding sitesalpha-bungarotoxin receptoralpha7 nicotinic acetylcholine receptoralpha7nAChRanti-epileptic agentsanti-epileptic drugsanti-hypertensionbiologicblood flow in brainbloodbrain barrierbody weight lossbrain atrophybrain blood circulationbrain blood flowbrain damagebrain-injuredcerebral atrophycerebral blood flowcerebral circulationcerebral vascularcerebro-vascularcerebrocirculationcerebrovascularcerebrovascular blood flowcholinergiccircadianclinical applicabilityclinical applicationclinical relevanceclinical testclinically relevantcognitive performancecontrast enhancedcortical atrophydepressiondisabilitydrug-resistant epilepsyexperimentexperimental researchexperimental studyexperimentsextracellularhigh blood pressurehospital dayshospital length of stayhospital stayhydrocephalichyperpiesiahyperpiesishypertensive diseasehypertensive disorderimplantationimprovedimproved outcomemicrovascular complicationsmicrovascular diseasemodel of animalmortalitymouse modelmurine modelneural controlneural regulationneuromodulationneuromodulatoryneuroregulationneutrophilnoveloptic imagingopticaloptical imagingpathwaypharmacologicpleiotropic effectpleiotropismpleiotropyresearch clinical testingresponsesexskull basesmall vessel diseasesurgerythrombotic diseasethrombotic disordertrial designvagus nerve stimulationwt-lossα7 nicotinic acetylcholine receptorα7nAChR
Get Agency plan to apply$29.99/mo · 7-day free trial · pipeline · alerts
or
— or —Get email alerts for similar roles
Description preview
Aneurysmal subarachnoid hemorrhage (SAH) carries high mortality in ~40% and poor outcomes in ~20% of all.
About 30% of patients who initially survive the rupture develop early brain injury and delayed cerebral ischemia,
both major causes of mortality, prolonged hospital stay, and disability. Microvascular dysfunction and vasospasm,
inflammation,…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click