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Nickel Cross-Coupling Cascades with α-Heteroatom Radicals to Prepare Sterically Hindered Alcohols and Amines
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Description preview
Project Summary
The overarching theme of this proposal is to apply robust and reliable reaction mechanisms to improve the
efficiency of forming C–C bonds adjacent to alcohol or amine functionality. Among the most common strategies
to these products is the addition of a Grignard reagent (or other carbon nucleophile) to a ketone or ketimine…
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