grant

New antiadipogenic drugs to reduce fibroadipogenic precursor cell differentiation process in DMD

Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
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Muscle degeneration in Duchenne muscular dystrophy (DMD) is characterized by loss of muscle fibers and its replacement by fat and fibrotic tissue. Fibro-adipogenic progenitors (FAPs), a type of skeletal muscle resident mesenchymal stem cells, are the main cause of fibro-fatty expansion. The molecular pathways driving the differentiation of human…

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New antiadipogenic drugs to reduce fibroadipogenic precursor cell differentiation process in DMD — UKRI | United Kingdom | Dev Procure