grant
Neurophysiological Correlates of Cognition Over Multi-Day Timescales in Epilepsy
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 1 Aug 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY202521+ years oldAddressAdultAdult HumanAdvisory CommitteesAffectAmmon HornAreaBenchmarkingBest Practice AnalysisBiometricsBiometryBiostatisticsBrainBrain Nervous SystemChronicClinical ResearchClinical StudyCognitionCognitiveCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalCommunication DisordersCommunication impairmentCommunicative DisordersCornu AmmonisCouplingDataDevelopmentDevicesDiagnosisDisturbance in cognitionEEGElectrodesElectroencephalogramElectroencephalographyElementsEncephalonEnvironmentEpilepsyEpileptic SeizuresEpilepticsFocal EpilepsyFocal Seizure DisorderFoundationsFunctional impairmentFundingFutureGoalsHippocampusHomeHumanImpaired cognitionImpairmentImplantInstitutionInterruptionInvestigationInvestigatorsK23 AwardK23 MechanismK23 ProgramKnowledgeLearningLocalization-Related EpilepsyMemoryMentored Patient-Oriented Research Career Development AwardMentored Patient-Oriented Research Career Development Award (K23)MentorshipMethodsModern ManMorbidityMorbidity - disease rateNINDSNREMNational Institute of Neurological Diseases and StrokeNational Institute of Neurological Disorders and StrokeNeurocognitiveNeuropsychologic TestsNeuropsychological TestsNeuropsychologiesNeuropsychologyPartial EpilepsiesPartial Seizure DisorderPatient AdmissionPatient RecruitmentsPatientsPatternPerformancePhysiciansProcessPrognosisQOLQOL improvementQuality of lifeResearchResearch MethodologyResearch MethodsResearch PersonnelResearchersScientistSeizure DisorderSeizuresSeriesSleepSleep disturbancesTask ForcesTemporal LobeTemporal Lobe EpilepsyTestingTimeTrainingWorkaberrant sleepadulthoodadvisory teambenchmarkco-morbidco-morbiditycognitive assessmentcognitive dysfunctioncognitive functioncognitive losscognitive neurosciencecognitive performancecognitive processcognitive testingcohortcomorbidityconferenceconventiondensitydevelopmentaldigitaldigital cognitive assessmentdigital cognitive testdigital tooldigital toolkitdisrupted sleepdisturbed sleepepilepsiaepilepsy monitoringepilepsy participantepilepsy patientepilepsy recordingepilepsy subjectepilepsy trackingepilepsy volunteerepileptic monitoringepileptic patientepileptic recordingepileptic subjectepileptiformepileptiform monitoringepileptiform recordingepileptiform trackingepileptogenicepileptogenic monitoringexperiencefrontal cortexfrontal lobehippocampalhomesimpaired sleepimprovedimprovements in QOLimprovements in quality of lifeinformation processinginnovateinnovationinnovativeinsightirregular sleeplife spanlifespanlong-term memorymemory consolidationmemory recallneocorticalneural networkneurocognitive disorderneurophysiologicalneurophysiologyneuropsychologicnon rapid eye movementnon-REMnon-rapid eye movementnonREMnonrapid eye movementnovelparticipant recruitmentpatient populationpatients with epilepsypreventpreventingprogramsprospectivequality of life improvementresearch and methodsseizure detectionseizure monitoringseizure recordingseizure trackingskillssleep disruptionsleep dysregulationsleep physiologysleep spindlesleep/wake disruptionsleep/wake disturbancesummitsymposiasymposiumtemporal cortextool
Description preview
PROJECT SUMMARY/ABSTRACT
Neurocognitive disorders in epilepsy are common and lead to significant morbidity and decline in quality
of life. While there are many tools to reduce seizures, our tools to manage cognitive dysfunction are limited. One
problem is that much of our understanding of cognitive impairment in epilepsy has been limited to short…
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