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Neuromuscular electrical stimulation for physical function maintenance during hematopoietic stem cell transplantation

Organization VA PUGET SOUND HEALTHCARE SYSTEMLocation SEATTLE, UNITED STATESPosted 1 Oct 2020Deadline 28 Feb 2026 ⚠️
VANIHUS FederalResearch GrantFY20262,4,D/2,4,5,TActive Follow-upAcuteAdherenceAdmissionAdmission activityAdverse ExperienceAdverse eventAfrican AmericanAfro AmericanAfroamericanAfter CareAfter-TreatmentAftercareAttenuatedAutologousB-Cell CLLB-Cell Chronic Lymphocytic LeukemiaB-Cell Chronic Lymphogenous LeukemiaB-Cell Chronic Lymphoid LeukemiaB-Cell Lymphocytic LeukemiaB-Lymphocytic LeukemiaBloodBlood Reticuloendothelial SystemBody CompositionBone MarrowBone Marrow GraftingBone Marrow Reticuloendothelial SystemBone Marrow TransplantBone Marrow TransplantationCOPDCancer TreatmentCancersCardiac Failure CongestiveChronic B-Lymphocytic LeukemiaChronic DiseaseChronic IllnessChronic Lymphatic LeukemiaChronic Lymphoblastic LeukemiaChronic Lymphocytic LeukemiaChronic Lymphogenous LeukemiaChronic Obstruction Pulmonary DiseaseChronic Obstructive Lung DiseaseChronic Obstructive Pulmonary DiseaseChronic cardiopulmonary diseaseChronic pulmonary heart diseaseClinicalClinical TrialsCongestive Heart FailureDEXADXADataDiagnosisDimensionsDiseaseDisorderDisuse AtrophyDual-Energy X-Ray AbsorptiometryDual-Energy Xray AbsorptiometryEORTCEquipment and supply inventoriesEthnic OriginEthnicityEuropean Organization for Research and Treatment of CancerExerciseExposure toFatigueFutureGoalsHSC transplantationHeart DecompensationHematologic CancerHematologic MalignanciesHematologic NeoplasmsHematological MalignanciesHematological NeoplasmsHematological TumorHematologyHematopoietic CancerHematopoietic Stem Cell TransplantHematopoietic Stem Cell TransplantationHistoryHodgkin DiseaseHodgkin DisorderHodgkin lymphomaHodgkin'sHodgkin's LymphomaHodgkin's diseaseHodgkins lymphomaHospital AdmissionHospitalizationInfectionInterventionInventoryJointsLaboratoriesLack of EnergyLeadLegLong-Term EffectsLymphaticMaintenanceMalignant Hematologic NeoplasmMalignant LymphogranulomaMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMarrow TransplantationMeasuresMedicalMultiple MyelomaMuscleMuscle AtrophyMuscle TissueMuscular AtrophyNauseaNon-Hodgkin's LymphomaNonhodgkins LymphomaOutcomeOxygen ConsumptionPatient Outcomes AssessmentsPatient Reported MeasuresPatient Reported OutcomesPatientsPb elementPhysiatric ProcedurePhysical FunctionPhysical Medicine ProcedurePhysical TherapeuticsPhysical activityPhysical therapyPhysiotherapyPlasma-Cell MyelomaPopulationProcess MeasureQOLQuality of lifeQuestionnairesRadiationRandomizedRecommendationRecording of previous eventsRecoveryReportingSafetySedentary behaviorSedentary life-styleSymptom BurdenSymptomsTestingTimeTransplantationVeteransWalkingactive followupagent orangeanti-cancer therapyattenuateattenuatesattenuationblood stem cell transplantationcancer therapycancer-directed therapychemotherapychronic cardiopulmonary conditionchronic cardiopulmonary disorderchronic cardiopulmonary dysfunctionchronic cardiopulmonary health conditionchronic disorderchronic heart failurechronic lymphoid leukemiachronic obstructive pulmonary disorderclinical careclinical validationco-morbidco-morbiditycombatcommon treatmentcomorbiditydecline in functiondecline in functional statusdeconditioningdecreased muscle massdetermine efficacyefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationelectromyostimulationevaluate efficacyexamine efficacyexperiencefollow upfollow-upfollowed upfollowupfunctional declinefunctional outcomesfunctional statusfunctional status declineheavy metal Pbheavy metal leadhematopoietic cell transplantationhematopoietic cellular transplantationhematopoietic progenitor cell transplantationhistoriesimprovedlow muscle massmalignancymuscle breakdownmuscle bulkmuscle degradationmuscle deteriorationmuscle formmuscle lossmuscle massmuscle strengthmuscle wastingmuscularmyelomamyelomatosisneoplasm/cancerneuromuscular Electrical Stimulationneuromuscular stimulationnon-Hodgkins diseasepost treatmentpreventpreventingprimary outcomerandomisationrandomizationrandomly assignedreduced muscle masssarcopeniasarcopenicsatisfactionsecondary outcomesedentarysedentary lifestyleside effectstandard of caretransplant

Applications closed.

Description preview

Hematopoietic cell transplantation (HCT) reduces physical function and muscle mass and increases fatigue.
Neuromuscular electrical stimulation (NMES), when used as a stand-alone intervention, improves muscle
strength and muscle mass in non-cancer patients with chronic obstructive pulmonary disease and chronic heart
failure. The use of NMES to…

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