grant
Neurology of Effortful Neutralization of Threat in Obsessive-Compulsive Disorder
Organization LAUREATE INSTITUTE FOR BRAIN RESEARCHLocation TULSA, UNITED STATESPosted 15 Sept 2017Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AddressAffectiveAttentionBehaviorBehavioralBiological MarkersCharacteristicsCorpus StriatumCorpus striatum structureDecision MakingDevelopmentDistressFunctional MRIFunctional Magnetic Resonance ImagingFunctional impairmentFundingHeterogeneityImpairmentIndividualKnowledgeLiteratureMeasuresMental HealthMental HygieneNeurobiologyNeurologyNeurosciencesObsessive-Compulsive DisorderObsessive-Compulsive NeurosisParticipantPatternPilot ProjectsProcessPsychiatric DiagnosisPsychological HealthResearchRestSafetySeveritiesSourceStimulusStriate BodyStriatumTreatment outcomebio-markersbiologic markerbiomarkercingulate cortexcompulsiondevelop therapydevelopmentaleffective therapyeffective treatmentexperimentexperimental researchexperimental studyexperimentsfMRIhealth assessmentimprovedintervention developmentneuralneural circuitneural circuitryneural imagingneural mechanismneuro-imagingneurobiologicalneurocircuitryneuroimagingneurological imagingneuromechanismnoveloutcome predictionpilot studypsychologicpsychologicalresponsestriatalsynaptic circuitsynaptic circuitrytherapy developmenttreatment development
Description preview
Obsessive-compulsive disorder (OCD) confers substantial individual and societal burden, and first-line
treatments are only effective in some of cases. One roadblock to treatment improvement is limited
understanding of compulsions, OCD’s characteristic behavioral patterns, which maintain distress and
contribute substantially to functional…
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