grant
Neurolinguistic development in 4 to 8 year-old late talkers with language delay
Organization VANDERBILT UNIVERSITYLocation Nashville, UNITED STATESPosted 1 Mar 2023Deadline 29 Feb 2028
NIHUS FederalResearch GrantFY20260-11 years old4 year old4 years of age6 year old6 years of age8 year old8 years of ageAgeBehavioralBiological MarkersBrainBrain Nervous SystemChildChild YouthChildren (0-21)CodeCoding SystemDWI (diffusion weighted imaging)DWI-MRIDataDevelopmentDevelopmental Disorder Speech or LanguageDevelopmental Language DisordersDiffusion MRIDiffusion Magnetic Resonance ImagingDiffusion Weighted MRIDiffusion weighted imagingDiffusion-weighted Magnetic Resonance ImagingDimensionsDorsalEarly InterventionEmotionalEncephalonExperimental DesignsFormulationFutureIndividual DifferencesInferiorInterventionJudgmentLanguageLanguage DelaysLanguage DevelopmentLanguage Development DisordersLeadLearningMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceModelingMorphologyNMR ImagingNMR TomographyNeurocognitiveNuclear Magnetic Resonance ImagingNursery SchoolsOutcomePathway interactionsPb elementPublishingResearchResearch SupportRestRetrospective StudiesRiskRoleSamplingSemanticsSpeechStandardizationSteamStreamStructureTestingTimeVocabularyVocabulary WordsWorkZeugmatographyacquiring language skillsage 4age 4 yearsage 6age 6 yearsage 8age 8 yearsage associated differenceage based differenceage dependent differenceage dependent variationage differenceage related differenceage related variationage specific differenceagesbehavior measurementbehavioral measurebehavioral measurementbio-markersbiologic markerbiomarkercohortcomputer based predictiondMRIdevelopmentaldiffer by agedifference across agedifference in agediffusion tensor imagingdorsal pathwaydorsal processing streamdorsal streamdorsal visual pathwaydorsal visual processing streamdorsal visual streameight year oldeight years of ageelementary schoolfour year oldfour years of agegrade schoolheavy metal Pbheavy metal leadinnovateinnovationinnovativeinterestkidslanguage abilitylanguage acquisitionlanguage learninglanguage skillsmulti-modal neuro-imagingmultimodal neuroimagingneuralneural imagingneuro-imagingneuroimagingneurological imagingnovelopen dataopen scienceopen-source datapathwayphonologypower analysispre-kpre-kindergartenpredictive biological markerpredictive biomarkerspredictive markerpredictive modelingpredictive molecular biomarkerpreschoolretrospective research studyretrospective surveyscreeningscreeningssemantic processingsix year oldsix years of ageskillssocial rolestructural imagingsubstantia albatheoriestractographyvariation by ageventral pathwayventral processing streamventral streamventral visual pathwayventral visual processing streamventral visual streamwhite matteryoungster
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PROJECT SUMMARY
Late talking is associated with negative academic and socio-emotional outcomes. Despite this, behavioral
measures are relatively poor at predicting who will end up having developmental language disorder. Moreover,
not much is known about either the typical neurocognitive changes associated with language development or
the brain…
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