grant
Neurobehavioral Effects of Frequent Co-use of Alcohol and Cannabis
Organization PENNSYLVANIA STATE UNIVERSITY, THELocation UNIVERSITY PARK, UNITED STATESPosted 30 Sept 2023Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025Active Follow-upAddressAeroseb-HCAlcohol Chemical ClassAlcohol DrinkingAlcohol co-useAlcohol consumptionAlcoholsBehaviorBehavioralBehavioral MechanismsBiologicalBloodBlood PlasmaBlood Reticuloendothelial SystemBrainBrain Nervous SystemCannabisCetacortConsumptionControl GroupsCorpus StriatumCorpus striatum structureCort-DomeCortefCortenemaCortisolCortisprayCortrilCuesDataDermacortDifferences between sexesDiffers between sexesDrug usageEcological momentary assessmentEldecortEncephalonEtOH drinkingEtOH useExhibitsFemaleFunctional MRIFunctional Magnetic Resonance ImagingFutureHeavy DrinkingHydrocortisoneHydrocortoneHytoneIndividualIndividual DifferencesInterventionKnowledgeLifeMarijuanaMeasurementMeasuresMechanisms of Behavior and Behavior ChangeNeuroendocrineNeuroendocrine SystemNeurosecretory SystemsNutracortOutcomeParticipantPathway interactionsPatternPersonsPlasmaPlasma SerumPreventionProcessProctocortReportingReticuloendothelial System, Serum, PlasmaRiskRisk FactorsRoleSamplingSex DifferencesSexual differencesStressStriate BodyStriatumSubstance Use DisorderTHC co-useTHC useTetrahydrocannabinol co-useTetrahydrocannabinol useTimeWorkactive followupalcohol and other drug usealcohol cravingalcohol ingestionalcohol intakealcohol polysubstance usealcohol product usealcohol responsealcohol usealcoholic beverage consumptionalcoholic drink intakebehavior mechanismbinge drinkerbiologicblood oxygen level dependentblood oxygenation level dependentbout drinkercannabis cravingcannabis legalizationcannabis usecannabis usercompare to controlcomparing females and malescomparing women and mencomparison controlcravingcue reactivitydrink heavilydrug useepisodic drinkerethanol consumptionethanol cravingethanol drinkingethanol ingestionethanol intakeethanol product useethanol responseethanol useexcessive alcohol consumptionexcessive alcohol ingestionexcessive alcohol intakeexcessive drinkingexcessive ethanol ingestionexperienceextreme drinkingfMRIfemales compared to malesfemales compared with malesfemales versus malesfemales vs. malesfollow upfollow-upfollowed upfollowupheavy alcohol uselegal marijuanalegalized cannabislegalized marijuanamalemarihuanamarijuana cravingmarijuana legalizationmarijuana usemarijuana userneuralneural imagingneuro-imagingneurobehavioralneuroimagingneurological imagingpathwaypreventpreventingprospectiverecruitresponseresponse to alcoholresponse to ethanolsecondary analysissexsex based differencessex-dependent differencessex-related differencessex-specific differencessocial rolestriatalsubstance usesubstance use and disordersubstance usersubstance usingtime intervalwomen compared to menwomen compared with menwomen versus menwomen vs. men♀♂
Description preview
Project Summary
Simultaneous use of alcohol and marijuana/cannabis (SAM) leads to increased craving, use, and
consequences compared to single use of either alcohol or cannabis. However, there is a dearth of knowledge
regarding the neural, neuroendocrine, and behavioral differences in SAM users that increases risk for these
negative outcomes. The…
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