grant
Multimodal AI Fusion Model for Early Detection for Pancreatic Cancer
Organization MAYO CLINIC ARIZONALocation SCOTTSDALE, UNITED STATESPosted 16 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025AbscissionAccountingAgeAlgorithmsAnxietyArizonaAssessment instrumentAssessment toolBiological MarkersBody CompositionCAT scanCT X RayCT XrayCT imagingCT scanCancer CauseCancer EtiologyCancersCessation of lifeClinicClinical DataClinical MarkersComputed TomographyComputerized Medical RecordConnectionist ModelsDataDeathDiabetes MellitusDiagnosisDiagnosticDiseaseDisorderDistressEarly DiagnosisEarly InterventionEarly treatmentElectronic Medical RecordEligibilityEligibility DeterminationEncapsulatedEngineeringEnsureExcisionExtirpationFloridaFutureGeneral PopulationGeneral PublicGeographic AreaGeographic LocationsGeographic RegionGeographical LocationGoalsGraphImageIncidenceIndividualMalignant NeoplasmsMalignant Pancreatic NeoplasmMalignant TumorMalignant neoplasm of abdomenMalignant neoplasm of pancreasMetabolic syndromeMetastasisMetastasizeMetastatic LesionMetastatic MassMetastatic NeoplasmMetastatic TumorMethodsMidwestMidwest U.S.Midwest USMidwestern United StatesMinorityModelingNatureNeoplasm MetastasisNeural Network ModelsNeural Network SimulationObesityOperative ProceduresOperative Surgical ProceduresOutcomePancreasPancreas CancerPancreas Ductal AdenocarcinomaPancreaticPancreatic CancerPancreatic Ductal AdenocarcinomaPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPerceptronsPerformancePredicting RiskProtocol ScreeningRemovalResistanceRiskRisk AssessmentRisk EstimateRisk FactorsScanningScreening procedureSecondary NeoplasmSecondary TumorSemanticsSiteSmokingSmoking StatusSocioeconomic FactorsSurgicalSurgical InterventionsSurgical ProcedureSurgical RemovalSurvival RateTechniquesTestingTimeTomodensitometryTrainingTumor BiologyUnited StatesUniversitiesValidationX-Ray CAT ScanX-Ray Computed TomographyX-Ray Computerized TomographyXray CAT scanXray Computed TomographyXray computerized tomographyabdominal CTabdominal cancerabdominal computed tomographyadiposityagesauto-segmentationautomated segmentationautomatic segmentationautosegmentationbio-markersbiologic markerbiomarkercancer metastasiscatscanchemo-/radio-therapychemo-radiotherapychemoradiationchemoradiation therapychemoradiation treatmentchemoradiotherapyclinical biomarkersclinical riskclinically useful biomarkerscohortcomputed axial tomographycomputer tomographycomputerized axial tomographycomputerized tomographycorpulencecostdeep learningdeep learning based modeldeep learning methoddeep learning modeldeep learning strategydiabetesearly detectionearly screeningearly therapyfederated learningforecasting riskgeographic disadvantagegeographic disparitygeographic inequalitygeographic inequitygeographic location disparitygeographic sitegraph attention networkgraph convolutional networkgraph neural networkhigh risk grouphigh risk individualhigh risk peoplehigh risk populationimagingimaging Segmentationimaging biomarkerimaging markerimaging-based biological markerimaging-based biomarkerimaging-based markerimprovedmalignancymulti-modal datamulti-modal datasetsmulti-modalitymultimodal datamultimodal data fusionmultimodal datasetsmultimodal fusionmultimodalityneoplasm/cancernon-contrast CTnoncontrast CTnoncontrast computed tomographynovelpancreatic malignancypatient oriented outcomespatient populationpatient screeningpatient subclasspatient subclusterpatient subgroupspatient subpopulationspatient subsetspatient subtypesprecancerprecancerouspredict riskpredict riskspredicted riskpredicted riskspredicting riskspredictive riskpredicts riskpremalignantprognosis modelprognosticprognostic abilityprognostic modelprognostic performanceprognostic powerprognostic utilityprognostic valueprospectiveradio-chemo-therapyradio-chemotherapyradiochemotherapyradiologistradiomicsrecruitresectionresistantrisk predictionrisk prediction algorithmrisk prediction modelrisk prediction systemrisk prediction toolrisk predictionsrisk stratificationscreeningscreening toolsscreeningssexsocial health determinantssocio-economic factorsstratify risksurgerytumortumor cell metastasisvalidations
Description preview
Pancreatic ductal adenocarcinoma (PDAC), accounting for 90% of all pancreatic cancers, is among the
deadliest, due largely to late-stage diagnosis and the aggressive nature of the disease. The critical challenge
lies in early detection, which is currently not viable for the general population due to low annual incidence and a significant risk of…
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