grant
Modulation of tendon mechanics by hyaluronic acid
Organization UNIVERSITY OF COLORADOLocation Boulder, UNITED STATESPosted 1 May 2026Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY202621+ years oldAblationAbscissionAdultAdult HumanAffectAgingAssayAttenuatedAutoregulationBackBindingBioassayBiochemicalBiological AssayBiologyBiopolymersBody TissuesCartilageCartilaginous TissueCell BodyCell-Extracellular MatrixCellsChondroitin ABC LyaseChondroitinase ABCCollagenCollagen FiberCollagen Type ICommunicationComplexCore ProteinCustomDMMBDataDevelopmentDigestionDisaccharidesDorsumDuran-Reynals Permeability FactorECMELISAEnzyme GeneEnzyme-Linked Immunosorbent AssayEnzymesExcisionExtensorExtirpationExtracellular MatrixExtracellular Matrix ProteinsFiberGL EnzymeGenerationsGlycansGlycosaminoglycansHomeostasisHyaglosidaseHyaluronate 4-glycanohydrolaseHyaluronate HydrolaseHyaluronic AcidHyaluronic Acid BindingHyaluronidaseHyaluronoglucosaminidaseHydrationHydration statusHydrogen OxideImageIncubatedIndividualInvestigationKnock-outKnockoutLaser ElectromagneticLaser RadiationLasersLengthLeucineLoad BearingMeasuresMechanicsMediatingMethacrylatesMethodologyMethodsMiceMice MammalsModelingMolecular InteractionMucopolysaccharidesMurineMusMuscleMuscle TissueOrthopedicOrthopedic Surgical ProfessionOrthopedicsPSGAGPathologicPenetrationPhysiologic pulsePhysiological HomeostasisPlayPolysaccharidesProteinsProteoglycanProteomicsPulseRecoveryRemovalRoleSHG imagingSlideStaining methodStainsStreptomycesStructureSurgical RemovalSwellingSystemTendinitisTendinopathyTendon structureTendonitisTendonsTestingTissuesTransmissionType 1 CollagenVisualizationWaterWeight BearingWeight-Bearing stateadulthoodagedaged miceaged mouseaggrecanattenuateattenuatesbonecell behaviorcellular behaviorchronic pain conditionchronic pain disorderchronic painful conditioncustomsdevelopmentaldimethylmethylene blueelderly miceenzyme linked immunoassayfluorophorefunctional restorationglycosaminoglycan polysulfateglycosaminoglycan polysulfuric acid esterglycosaminoglycan polysulphatehydrophilicityimaginginsightlubricating glycoprotein-Ilubricinmechanicmechanicalmechanical behaviormonomermultiphoton excitation microscopymultiphoton microscopymuscularold micepolysulfated glycosaminoglycanpressureregeneration based therapyregeneration therapyregenerative therapeuticsregenerative therapyrepairrepairedresectionresponserestore functionrestore functionalityrestore lost functionsecond harmonicsecond harmonic generation imagingsocial rolesoft tissuesulfated glycosaminoglycantransmission processversican
Description preview
PROJECT SUMMARY
There is a need to understand how deviations in glycosaminoglycan (GAG) content affect fiber level-
mechanics so we can better inform regenerative therapies that aim to restore function to tendinopathic and aged
tendons. Various studies investigating the influence of GAGs and proteoglycans (PGs) on tendon mechanics at
the fiber…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click