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Microbiome Discovery and Mechanisms to Combat Antibiotic Resistance at Mucosal Surfaces
Organization BAYLOR COLLEGE OF MEDICINELocation HOUSTON, UNITED STATESPosted 1 Mar 2021Deadline 28 Feb 2026 ⚠️
NIHUS FederalResearch GrantFY2025Active SitesAddressAlimentary CanalAnti-Bacterial AgentsAntibiotic AgentsAntibiotic DrugsAntibiotic ResistanceAntibioticsBacteriaBacterial Antibiotic ResistanceBacterial InfectionsBacteriophagesBenignBiologyBionomicsC diffC difficileC. diffC. difficileCOVID crisisCOVID epidemicCOVID pandemicCOVID-19 crisisCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 yearsCause of DeathCessation of lifeChemical StructureChemicalsChronicClinicClinicalClinical TrialsClostridioides difficileClostridium difficileCombating Antibiotic Resistant BacteriaCommunicable DiseasesCommunitiesComplexDNA mutationDeathDevelopmentDigestive TractDiseaseDisorderDrug resistanceDrugsESKAPEESKAPE pathogensEarthEcologyEffectivenessEnvironmentEnzyme GeneEnzymesEquilibriumFailureGI TractGI colonizationGastrointestinal TractGastrointestinal tract structureGenesGeneticGenetic ChangeGenetic defectGenetic mutationGenitourinaryGenitourinary systemHealthHistoryHorizontal Gene TransferHumanIncentivesIndividualInfectionInfection preventionInfectious DiseasesInfectious DisorderJobsLateral Gene TransferLearningLifeMRSAMeasuresMedicationMethicillin Resistant S. AureusMethodsMiscellaneous AntibioticModelingModern ManModern MedicineMucosaMucosal TissueMucous MembraneMutationNasalNasal EpitheliumNasal Passages NoseNatureNoseOccupationsOrganoidsOutcomePatientsPhagesPharmaceutical PreparationsPlanet EarthPrevent infectionPreventative strategyPrevention strategyPreventive strategyProcessProfessional PositionsPropertyPublic HealthRecording of previous eventsResearchResistanceResistance developmentResistance to antibioticsResistant S. PneumoniaeResistant Streptococcus pneumoniaeResistant developmentResistant to antibioticsRespiratory System, Nose, Nasal PassagesSARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 pandemicSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicScientistSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 pandemicSurfaceTestingTherapeuticTransmissionTransplantationUncertaintyUrogenitalUrogenital SystemVaccinesValidationVirusWorkalimentary tractantagonismantagonistanti-bacterialanti-microbialantibiotic drug resistanceantibiotic resistantantibiotic resistant bacteriaantibiotic resistant infectionsantibiotic resistant pathogenantimicrobialbacteria infectionbacteria pathogenbacterial antibiotic resistantbacterial diseasebacterial pathogenbacterial resistance to antibioticbacterial virusbalancebalance functionbeneficial florabeneficial microbesbeneficial microflorabeneficial microorganismclinical practicecombatcommunity microbescoronavirus disease 2019 crisiscoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease-19 global pandemiccoronavirus disease-19 pandemicdepositorydeveloping resistancedevelopmentaldigestive canaldoubtdrug resistantdrug resistant pathogendrug/agentemerging pathogenexperiencefecal microbial transplantationfecal microbiome transplantationfecal microbiota transplantfecal microbiota transplantationfecal transplantfecal transplantationfightinggastrointestinal tract colonizationgenome mutationgut colonizationhigh riskhigh risk grouphigh risk individualhigh risk peoplehigh risk populationhistoriesinnovateinnovationinnovativeintestinal colonizationmethicillin resistance Staphylococcus aureusmethicillin resistant Staphylococcus aureusmethicillin resistant strains of Staphylococcus aureusmicrobe communitymicrobialmicrobial communitymicrobial consortiamicrobial floramicrobiomemicrobiome interventionmicrobiome therapeuticsmicrobiome therapymicrobiome treatmentmicrobiome-based interventionmicrobiome-based therapeuticmicrobiome-based therapymicrobiome-based treatmentmicrobiotamicrobiota compositionmicrofloramicroorganism communitymucosal sitemultispecies consortianasal microbial communitynasal microbiotanew drug treatmentsnew drugsnew pathogennew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovelnovel drug treatmentsnovel drugsnovel pathogennovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapypandemicpandemic diseasepathobiontpathogenpathogenic E colipathogenic E. colipathogenic Escherichia colipathogenic bacteriapolymicrobial communitypre-clinicalpreclinicalpressurepreventpreventingprogramsprophylacticrepositoryresistance strainresistance to Drugresistantresistant strainresistant strains of S. Pneumoniaeresistant to Drugsevere acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicsinonasal microbiotasynergismtooltransmission processtransplanturgent and serious threaturgent or serious threatvalidationsviral pandemic
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Overall Project Summary
The ability to control bacterial infections with antibiotics has been one of the most important public health
advancements in human history. Before the discovery of antibiotics and vaccines, infectious disease was the
leading cause of death and constituted nearly 50% of deaths in the US alone. Now, infectious diseases as a…
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