grant
METABOLIC REPROGRAMMING AND PULMONARY VASCULAR DISEASE ASSOCIATED WITH CONGENITAL HEART DISEASE RESULTING IN INCREASED PULMONARY BLOOD FLOW
Organization FLORIDA INTERNATIONAL UNIVERSITYLocation MIAMI, UNITED STATESPosted 10 Aug 2020Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY20250-11 years oldAnabolismApoptoticApplications GrantsArteriesAttenuatedBasal Transcription FactorBasal transcription factor genesBioenergeticsBlood VesselsBlood flowCardiac MalformationCell BodyCell Communication and SignalingCell Growth in NumberCell MultiplicationCell ProliferationCell SignalingCellsCellular ProliferationCellular RegulationChildChild YouthChildhoodChildren (0-21)ClinicalCollagenComplexCongenital Cardiac DefectsCongenital Heart DefectsDataDepositDepositionDevelopmentE3 LigaseE3 Ubiquitin LigaseElectron TransportEndotheliumEnsureEventFundingGene Down-RegulationGeneral Transcription Factor GeneGeneral Transcription FactorsGlnGlutamineGrant ProposalsHeart MalformationHumanIndividualIntermediary MetabolismIntracellular Communication and SignalingInvestigationJUN Family GeneJUN Proto-oncogene FamilyJUN geneKinasesKnowledgeL-GlutamineL-ProlineLinkLung ParenchymaLung TissueMechanicsMediatingMetabolicMetabolic PathwayMetabolic ProcessesMetabolismMitochondriaModelingModern ManMorphologyOxidative PhosphorylationOxidative Phosphorylation PathwayP01 MechanismP01 ProgramPathologicPathologyPathway interactionsPeptidyl Prolyl HydroxylasePhenotypePhosphotransferase GenePhosphotransferasesPhosphotyrosinePost-Translational Modification Protein/Amino Acid BiochemistryPost-Translational ModificationsPost-Translational Protein ModificationPost-Translational Protein ProcessingPosttranslational ModificationsPosttranslational Protein ProcessingProcessProcollagen Prolyl 4-HydroxylaseProcollagen-Proline DioxygenaseProgram Project GrantProgram Research Project GrantsProlineProline HydroxylaseProline,2-Oxoglutarate 4-DioxygenaseProlyl 4-HydroxylaseProlyl HydroxylaseProtein ModificationProtocollagen Prolyl HydroxylasePublishingQ LevoglutamideQ. LevoglutamideResearchResearch Peer ReviewResearch Program ProjectsRoleSOX18SOX18 geneSRY-Box 18ShuntShunt DeviceSignal PathwaySignal TransductionSignal Transduction SystemsSignalingStructure of parenchyma of lungTranscription Factor Proto-OncogeneTranscription RepressionTranscription factor genesTransphosphorylasesTyrosine-O-phosphateUbiquitin Protein LigaseUbiquitin-Protein Ligase ComplexesUbiquitin-Protein Ligase E3Vascular DiseasesVascular DisorderVascular remodelingWorkabnormal heart developmentadvanced diseaseadvanced illnessaerobic glycolysisangiogenesisarterioleattenuateattenuatesbiological signal transductionbiosynthesisblood vessel disorderc junc-jun Genecell growth regulationcompare to controlcomparison controlcongenital cardiac abnormalitycongenital cardiac anomaliescongenital cardiac diseasecongenital cardiac disordercongenital cardiac malformationcongenital heart abnormalitycongenital heart anomalycongenital heart diseasecongenital heart disordercongenital heart malformationcustomized therapycustomized treatmentdevelopmentaldisease phenotypeelectron transferendothelial dysfunctiongene repressionimpaired pulmonary vascularizationimprovedindividualized medicineindividualized patient treatmentindividualized therapeutic strategyindividualized therapyindividualized treatmentinterestkidslung vascular diseaselung vascular injurymechanicmechanicalmechanical propertiesmitochondrialnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynovelnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachpathwaypatient specific therapiespatient specific treatmentpediatricprogramspulmonarypulmonary arterial stiffeningpulmonary arterial stiffnesspulmonary artery stiffeningpulmonary artery stiffnesspulmonary vascular diseasepulmonary vascular disorderpulmonary vascular dysfunctionpulmonary vascular injurypulmonary vasculopathyresponseshuntssocial rolesynergismtailored medical treatmenttailored therapytailored treatmenttranscription factortranslational investigatortranslational researchertranslational scientistubiquitin-protein ligaseunique treatmentvascularvascular dysfunctionvasculopathyyoungster
Get Agency plan to apply$29.99/mo · 7-day free trial · pipeline · alerts
or
— or —Get email alerts for similar roles
Description preview
PROGRAM SUMMARY
Pulmonary vascular disease (PVD) is one of the most critical complications of children born with congenital heart
disease (CHD) that results in increased pulmonary blood flow (PBF). Metabolic reprogramming is increasingly
recognized as a critical component of early pulmonary vascular injury and disease. Vascular morphology studies…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click