grant
MechanoROS-T: Exploring mechanoregulated hydrogen peroxide as a mechanism of T cell activation
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
T cells mediate immune responses against infection. They scan our tissues for foreign antigens that that are recognised by cell surface
T cell receptors (TCRs). Antigen-TCR binding initiates signalling cascades to promote effector functions including cytokine release,
proliferation and cytotoxicity. Insights into T cell signalling are key to…
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