grant
Mechanisms regulating inflammatory fibroblasts in wound healing
Organization UNIVERSITY OF VIRGINIALocation CHARLOTTESVILLE, UNITED STATESPosted 1 Sept 2025Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025AddressBiocompatible MaterialsBiologyBiomaterialsBody TissuesCell BodyCell Communication and SignalingCell SignalingCell-Extracellular MatrixCellsCessation of lifeChronicCuesDeathDiseaseDisorderECMExtracellular MatrixFibroblastsFibrosisHealthHumanImmuneImmune infiltratesImmunesInflammationInflammatoryIntracellular Communication and SignalingMediatingModern ManMyofibroblastPathogenesisPathway interactionsPhenotypePopulationProcessRegulationResolutionRoleSignal TransductionSignal Transduction SystemsSignalingTherapeuticTissuesWestern WorldWorkWound RepairWound modelsbiological materialbiological signal transductioncandidate biomarkercandidate markercytokineimmune cell infiltratein vivo Modelinsightpathwayrecruitresolutionssocial rolespatial and temporalspatial temporalspatiotemporaltissue repairwound healingwound healing modelswound recoverywound resolution
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Description preview
Project Summary
Wound healing is a central aspect of human health that is a coordinated process involving multiple cell
populations. Interactions between the microenvironment, recruited cell populations, and tissue-resident cell
populations, in particular stromal and immune cell populations, is critical for successful wound healing.
Dysregulated…
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