grant
Mechanisms and Modifiers of Prenatal Acetaminophen Exposure and Child Neurodevelopment
Organization UNIVERSITY OF WASHINGTONLocation SEATTLE, UNITED STATESPosted 1 Apr 2026Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY20260-11 years oldAD/HDADHDAPAPAccountingAcetamidophenolAcetaminophenAcetominophenAdolescent PsychiatryAffectAllelesAllelomorphsAmericanAnimal Experimental UseAnimal ExperimentationAnimal ResearchAnimalsAsian groupAsian individualAsian peopleAsian populationAsiansAttention deficit hyperactivity disorderAwardBiologicalBiological MarkersBloodBlood - brain barrier anatomyBlood Reticuloendothelial SystemBlood-Brain BarrierBrainBrain Nervous SystemCausalityCells Placenta-TissueChildChild HealthChild PsychiatryChild PsychologyChild YouthChildren (0-21)ClinicClinical TrialsCounselingCountryDataDevelopmentDiseaseDisorderDoctor of PhilosophyDrugsEncephalonEnvironmentEpidemiologic ResearchEpidemiologic analysisEpidemiologyEtiologyEuropeanExposure toFellowshipFetusFeverFood and Drug AdministrationFutureGene set enrichment analysisGene variantGenesGeneticGenetic RiskGenomeGenomicsGenotypeGestationGoalsHarm MinimizationHarm ReductionHemato-Encephalic BarrierHepatotoxic effectHepatotoxicityHeritabilityHeterogeneityHydroxyacetanilideIndividualInterventionKnowledgeLeadLearningLinkLiteratureLiver ToxicityMeasurementMeasuresMediatingMedical Care CostsMedicationMedicineMental health promotionMentorsMetabolicMethodsModelingMolecularMultiomic DataNeural DevelopmentNeurodevelopmental DisorderNeurological Development DisorderNeuropsychologiesNeuropsychologyNormal PlacentomaOutcomeOutcome StudyOxidation-ReductionPainPainfulParacetamolPathologyPathway interactionsPb elementPediatric PsychologyPediatricsPh.D.PhDPharmaceutical PreparationsPharmaceuticsPharmaciesPharmacogeneticsPharmacogenomicsPharmacy (field)Pharmacy facilityPhasePlacentaPlacenta Embryonic TissuePlacentomePopulationPositionPositioning AttributePostdocPostdoctoral FellowPredominantly Hyperactive-Impulsive Type Attention-Deficit DisorderPredominantly Hyperactive-Impulsive Type Hyperactivity DisorderPregnancyPregnant WomenPrevalencePreventionPreventiveProcessProspective StudiesPsychiatristPsychiatryPsychopathologyPyrexiaQOLQuality of lifeRecommendationRedoxRegression AnalysesRegression AnalysisRegression DiagnosticsReportingResearchResearch AssociateRiskSafetySchoolsSeriesSiteStatistical RegressionSubgroupSubstance abuse problemTechniquesTestingTherapeuticToxic effectToxic effect on liver cellsToxicitiesTrainingUSFDAUnited StatesUnited States Food and Drug AdministrationVariantVariationWorkabnormal psychologyabuse of substancesallelic variantanimal experimentationsassociate facultyassociate professorbio-markersbiologicbiologic markerbiomarkerbloodbrain barriercareercausationchild developmental psychologycohortdata integrationdecreased incomedevelop therapydevelopmentaldisease causationdrug/agentepidemiologicepidemiologic evaluationepidemiologic investigationepidemiologicalexpectant motherexpectant womenexpecting motherexpecting womenexperienceexposed in uterofebrilefebrisfetalfetal bloodfetal exposuregenetic variantgenome scalegenome-widegenomewidegenomic variantheavy metal Pbheavy metal leadhepatic toxicityhepatoxicityin utero exposureincome lossindividuals who are pregnantinsightintervention developmentintra-uterine environmental exposureintrauterine environmental exposureinvestigate epidemiologykidslost earninglost incomelost wagemedical costsmedical expensesmeetingmeetingsmetabolism measurementmetabolomemetabolomicsmetabonomemetabonomicsmid-career facultymidcareer facultyminimal riskmolecular biomarkermolecular markermultidisciplinarymultiomicsmultiple omic datamultiple omicsneurobehavioral disorderneurodevelopmentneurodevelopmental diseaseneuron toxicityneuronal toxicityneuropsychiatricneuropsychiatryneuropsychologicneurotoxicneurotoxicitynon targeted analysisnontargeted approachnontargeted methodnontargeted techniqueoxidation reduction reactionpanomicspathwaypeople who are pregnantpharmaceuticpost-docpost-doctoralpost-doctoral traineeprecision medicineprecision-based medicinepregnant femalespregnant motherspregnant peoplepregnant populationsprenatalprenatal exposureprenatally exposedpreventpreventingprospective research studyprospective surveypublic health prioritiesreduced incomeresearch associatesskill acquisitionskill developmentskillsstatisticsstudy epidemiologysubstance abusesuicide ratesurvey epidemiologytherapy developmentthose who are pregnanttooltraining opportunitytranscriptomicstreatment developmentunbornuntargeted analysisuntargeted analytical approachuntargeted analytical methoduntargeted analytical techniqueuntargeted approachuntargeted investigationsuntargeted methoduntargeted strategyuntargeted techniquewomen who are pregnantyoungster
Description preview
PROJECT SUMMARY
Acetaminophen, which is found in more than 600 prescription and non-prescription medications for mild to
moderate pain and fever reduction, is not restricted to pharmacies and is sold over-the-counter in many countries,
including the United States. In most populations worldwide, over 50% of pregnant people report taking…
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