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Mapping dynamic functional networks across environments and backgrounds

Organization UNIVERSITY OF TORONTOLocation TORONTO, CANADAPosted 26 Sept 2010Deadline 31 Jan 2026 ⚠️
NIHUS FederalResearch GrantFY2025AddressAllelesAllelomorphsAssayBaker's YeastBioassayBiologicalBiological AssayBrewer's YeastBudding YeastCRISPR approachCRISPR based approachCRISPR methodCRISPR methodologyCRISPR techniqueCRISPR technologyCRISPR toolsCRISPR-CAS-9CRISPR-based methodCRISPR-based techniqueCRISPR-based technologyCRISPR-based toolCRISPR/CAS approachCRISPR/Cas methodCRISPR/Cas technologyCRISPR/Cas9CRISPR/Cas9 technologyCas nuclease technologyCell BodyCell CycleCell Division CycleCell FunctionCell PhysiologyCell ProcessCellsCellular FunctionCellular MorphologyCellular PhysiologyCellular ProcessChromosome MappingClustered Regularly Interspaced Short Palindromic Repeats approachClustered Regularly Interspaced Short Palindromic Repeats methodClustered Regularly Interspaced Short Palindromic Repeats methodologyClustered Regularly Interspaced Short Palindromic Repeats techniqueClustered Regularly Interspaced Short Palindromic Repeats technologyCollectionComplexData SetDependenceDiseaseDisorderEndomycetalesEnvironmentEssential GenesEukaryotaEukaryoteEukaryotic CellExperimental DesignsFundingGene DeletionGene LocalizationGene MappingGene Mapping GeneticsGene variantGenesGeneticGenetic DeterminismGenetic DiversityGenetic VariationGenetic studyGenomeGenotypeGrantHereditaryHereditary DiseaseHeritabilityHumanHuman Cell LineHuman Gene MappingHuman Gene Mapping DNA SequencingHuman GeneticsHuman GenomeHuman genetic mappingImageImage AnalysesImage AnalysisInborn Genetic DiseasesIndividualInheritedInherited disorderLinkLinkage MappingMalignant CellMapsMeasurementMethodsModelingModern ManMorphologyOutcomePhenotypePlayPositionPositioning AttributePrevalencePropertyProteomeResearchResearch ResourcesResourcesRoleS cerevisiaeS. cerevisiaeSaccharomyces cerevisiaeSaccharomycetalesStressStructureSubcellular ProcessTestingTotal Human and Non-Human Gene MappingVariantVariationWorkYeastsallelic variantbiologiccancer cellcell imagingcell morphologycellular imagingdata toolsdesigndesigningfitnessgene deletion mutationgene functiongene interactiongenetic analysisgenetic determinantgenetic mappinggenetic variantgenome scalegenome sequencinggenome-widegenomewidegenomic varianthereditary disorderheritable disorderhuman diseasehuman whole genomeimage evaluationimage interpretationimagingimaging platformimprovedinborn errorinherited diseasesinherited genetic diseaseinherited genetic disorderinnovateinnovationinnovativeinsightmembermutantpersonalization of treatmentpersonalized medicinepersonalized therapypersonalized treatmentpopulation basedprotein complexresponsescaffoldscaffoldingscreeningscreeningssocial roletemperature sensitive mutanttraityeast genetics

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Description preview

Genome sequencing has provided an unprecedented view into the extent of human genetic variation. Yet, our ability to link
specific genetic variants to phenotypes remains limited. Moreover, genetic interactions between complex combinations of
variants likely contribute to the challenge. To discover rules governing genetic interaction networks, we…

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Mapping dynamic functional networks across environments and backgrounds — UNIVERSITY OF TORONTO | CANADA | Sept 2010 | Dev Procure