grant
Longitudinal Effects of E-cigarette Use on Cardiovascular and Pulmonary Health
Organization UNIVERSITY OF WISCONSIN-MADISONLocation MADISON, UNITED STATESPosted 6 Sept 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY2025Active Follow-upAdverse effectsAffectAgeAirAlcohol Chemical ClassAlcoholsAmericanAreaArteriesB cell differentiation factorB cell stimulating factor 2B-Cell Differentiation FactorB-Cell Differentiation Factor-2B-Cell Stimulatory Factor-2BCDFBMIBMI percentileBMI z-scoreBSF-2BSF2Biological MarkersBlood GlucoseBlood PressureBlood SampleBlood SugarBlood specimenBody WeightBody mass indexC-reactive proteinCAT scanCT X RayCT XrayCT imagingCT scanCannabisCarbon MonoxideCardiac ChronotropismCardiopulmonaryCardiovascularCardiovascular Body SystemCardiovascular DiseasesCardiovascular Organ SystemCardiovascular systemChronicComputed TomographyCotinineDecision MakingDependenceDiameterDiseaseDisorderElectronic Nicotine Delivery ProductElectronic Nicotine Delivery SystemsEndogenous Nitrate VasodilatorEndotheliumEndothelium-Derived Nitric OxideEthnic OriginEthnicityExhalationExhalingF2-IsoprostanesFEV1FEV1%VCFastingForced Expiratory Volume 1 TestForced Expiratory Volume in 1 SecondFundingFutureGenderGlassGlycohemoglobin AGlycosylated hemoglobin AHPGFHb A1Hb A1a+bHb A1cHbA1HbA1cHealthHealth PolicyHealth StatusHeart RateHeart VascularHemi-MyeloperoxidaseHemoglobin A(1)Hepatocyte-Stimulating FactorHumulin RHybridoma Growth FactorIFN-beta 2IFNB2IL-6IL6 ProteinImageInflammationInsulinInsulin ResistanceInterleukin-6LearningLeukocyte CountLeukocyte NumberLevel of HealthLinkLipidsLong-Term EffectsLungLung DiseasesLung Respiratory SystemMGI-2MeasuresMediatingMethodsMononitrogen MonoxideMorbidityMorbidity - disease rateMyeloid Differentiation-Inducing ProteinMyeloperoxidaseNicotineNicotine DependenceNitric OxideNitrogen MonoxideNitrogen ProtoxideNovolin ROrganism-Level ProcessOrganismal ProcessOxidative StressPFT/FEV1ParticipantPatientsPatternPeroxidasesPersonsPhenotypePhysiologic ProcessesPhysiological ProcessesPlasmacytoma Growth FactorPoliciesProbabilityProteins, specific or class, C-reactivePublic HealthPulmonary DiseasesPulmonary DisorderPulmonary Function Test/Forced Expiratory Volume 1Quetelet indexRaceRacesRecoveryRegular InsulinResearchResearch ProposalsResidual volumeRespiratory ExpirationRiskRisk ReductionSamplingScienceScotineShapesSmoking HistorySpirometryStandardizationStress TestsStructureSympathetic Nervous SystemTHC co-useTHC useTetrahydrocannabinol co-useTetrahydrocannabinol useTextureTimeTobacco smokingTobacco smoking behaviorTobacco-Associated CarcinogenTomodensitometryTotal Lung CapacityTransmissionUnited StatesWeightWhite Blood Cell CountWhite Blood Cell Count procedureX-Ray CAT ScanX-Ray Computed TomographyX-Ray Computerized TomographyXray CAT scanXray Computed TomographyXray computerized tomographyYouthYouth 10-21active followupagesbio-markersbiologic markerbiomarkerbrachial arterycannabis usecardiometaboliccardiometabolismcardiovascular disordercardiovascular healthcarotid intima-media thicknesscatscancigarette smokingcigarette usecirculatory systemcohortcombustible cigarettecomputed axial tomographycomputer tomographycomputerized axial tomographycomputerized tomographycone-beam CTcone-beam computed tomographyconventional cigarettedisease of the lungdisease riskdisorder of the lungdisorder riske-cig usee-cigarette useecig useecigarette useelectronic cigarette useelectronic nicotine delivery deviceelectronic nicotine distribution systemendothelial cell derived relaxing factorexercise capacityexperimental groupfastedfastsfollow upfollow-upfollowed upfollowuphealth care policyhealth levelheart rate variabilityhemoglobin A1cimagingindexinginsightinsulin resistantinsulin toleranceinterestinterferon beta 2intima medial thickeningintima-media thicknessintimal medial thickeninglung disorderlung healthmarijuana usemortalitynew markernicotine addictionnicotine dependentnon-contrast CTnoncontrast CTnoncontrast computed tomographynovel biomarkernovel markerpack/yearpressurepulmonarypulmonary healthracialracial backgroundracial originrecruitreduce riskreduce risksreduce that riskreduce the riskreduce these risksreduces riskreduces the riskreducing riskreducing the riskrisk-reducingsystemic inflammationsystemic inflammatory responsetobacco carcinogentobacco related carcinogentobacco specific carcinogentraditional cigarettetransmission processtreadmillultrasoundurinaryvolume CTvolume computed tomographyvolumetric computed tomographywaist circumferenceweightsyouth age
Description preview
PROJECT SUMMARY
Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however, we do not
understand their long-term health effects. Although ENDS use delivers far lower levels of carcinogens than
tobacco smoking, very little is known about whether ENDS use affects the risks of developing cardiovascular
(CV) or pulmonary…
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