grant
Long-term Neuropsychiatric Sequelae of SARS-CoV-2 Infection in Late Life
Organization NORTHERN CALIFORNIA INSTITUTE/RES/EDULocation SAN FRANCISCO, UNITED STATESPosted 1 Apr 2023Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY20252019 novel corona virus2019 novel coronavirus2019-nCoV21+ years old65 and older65 or older65 years of age and older65 years of age or more65 years of age or older65+ years65+ years oldAD related dementiaADRDAcuteAdmissionAdmission activityAdultAdult HumanAffective DisordersAgeAged 65 and OverAlzheimer risk factorAlzheimer's and related dementiasAlzheimer's dementia and related dementiaAlzheimer's dementia or related dementiaAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementiaAlzheimer's disease related dementiaAlzheimer's disease riskAmentiaAmericanAnosmiaAnxiety DisordersBehavioralBlood VesselsBrainBrain Nervous SystemCNS Nervous SystemCOVID diagnosisCOVID disease severityCOVID infected patientCOVID patientCOVID positive patientCOVID severityCOVID survivorsCOVID testCOVID testsCOVID-19COVID-19 affectedCOVID-19 consequenceCOVID-19 diagnosisCOVID-19 disease severityCOVID-19 effectCOVID-19 impactCOVID-19 impactedCOVID-19 induced neurocognitive dysfunctionCOVID-19 infected patientCOVID-19 infectionCOVID-19 infection survivorsCOVID-19 negativeCOVID-19 neurocognitive consequencesCOVID-19 neurocognitive impactsCOVID-19 neurocognitive manifestationsCOVID-19 neurocognitive sequelaeCOVID-19 patientCOVID-19 positive patientCOVID-19 related cognitive declineCOVID-19 severityCOVID-19 survivorsCOVID-19 testCOVID-19 testsCOVID-19 virusCOVID-19 virus infectionCOVID19 diagnosisCOVID19 disease severityCOVID19 infectionCOVID19 negativeCOVID19 patientCOVID19 positive patientCOVID19 severityCOVID19 virusCV-19Care GiversCaregiversCase StudyCenters for Medicare and Medicaid ServicesCentral Nervous SystemCephalalgiaCephalgiaCephalodyniaClinicalCoV-2CoV2CodeCoding SystemCoronavirus Infectious Disease 2019Cranial PainDataData LinkagesData SourcesDementiaDevelopmentDiagnosisDiseaseDisease ManagementDisorderDisorder ManagementDrugsEarly InterventionEncephalonEpidemiologyEventFunctional impairmentGeographyGoalsHead PainHeadacheHealthHealth Care Financing AdministrationHealth Care SystemsHealth Insurance for Aged and Disabled, Title 18Health Insurance for Disabled Title 18Health ServicesHistoryHospital AdmissionHospitalizationImmune responseIncidenceIndividualInfectionInternational Classification of DiseasesInternational Statistical Classification of Diseases and Related Health ProblemsIntervention StrategiesKnowledgeLaboratoriesLinkMedicalMedicareMedicationMental HealthMental HygieneMental disordersMental health disordersMood DisordersNatureNerve DegenerationNervous System DiseasesNervous System DisorderNeuraxisNeurologicNeurologic DisordersNeurologicalNeurological DisordersNeuron DegenerationNewly DiagnosedNursing HomesOutcomeOutcome AssessmentPatientsPharmaceutical PreparationsPhasePhenotypePoliciesPolymerase Chain ReactionPreventative strategyPrevention strategyPreventive strategyPsyche structurePsychiatric DiseasePsychiatric DisorderPsychological HealthPsychological ImpactPsychosesPublic HealthPublishingRecord Linkage StudyRecording of previous eventsRecoveryReportingResearchRiskRisk AdjustmentRisk FactorsSARS corona virus 2SARS-CO-V2SARS-COVID-2SARS-CoV-2SARS-CoV-2 diagnosisSARS-CoV-2 disease severitySARS-CoV-2 infected patientSARS-CoV-2 infectionSARS-CoV-2 negativeSARS-CoV-2 neurocognitive sequelaeSARS-CoV-2 patientSARS-CoV-2 positive patientSARS-CoV-2 severitySARS-CoV-2 survivorsSARS-CoV-2 testSARS-CoV-2 testsSARS-CoV2SARS-CoV2 infectionSARS-associated corona virus 2SARS-associated coronavirus 2SARS-coronavirus-2SARS-related corona virus 2SARS-related coronavirus 2SARSCoV2SamplingSevere Acute Respiratory Coronavirus 2Severe Acute Respiratory Distress Syndrome CoV 2Severe Acute Respiratory Distress Syndrome Corona Virus 2Severe Acute Respiratory Distress Syndrome Coronavirus 2Severe Acute Respiratory Syndrome CoV 2Severe Acute Respiratory Syndrome-associated coronavirus 2Severe Acute Respiratory Syndrome-related coronavirus 2Severe acute respiratory syndrome associated corona virus 2Severe acute respiratory syndrome coronavirus 2Severe acute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome related corona virus 2Social ImpactsSourceStatistical MethodsSymptomsTitle 18United States Centers for Medicare and Medicaid ServicesUnited States Department of Veterans AffairsUnited States Health Care Financing AdministrationUnited States Veterans AdministrationVeteransVeterans AdministrationVeterans AffairsVeterans Health AdministrationVeterans Health AffairsWuhan coronavirusabove age 65acute symptomadulthoodadverse consequenceadverse outcomeafter COVID-19 infectionafter SARS-CoV-2 infectionafter SARS-CoV2 infectionafter age 65after infection by SARS-CoV-2after severe acute respiratory distress syndrome CoV-2 infectionage 65 and greaterage 65 and olderage 65 or olderageage associatedage associated neurodegenerationage associated neurodegenerative diseaseage associated neurodegenerative disorderage correlatedage dependentage dependent neurodegenerationage dependent neurodegenerative conditionage dependent neurodegenerative diseaseage dependent neurodegenerative disorderage linkedage of 65 years onwardage relatedage related neurodegenerationage specificage-driven neurodegenerative disordersage-related neurodegenerative diseaseage-related neurodegenerative disorderaged 65 and greateraged 65+aged ≥65agesaging associatedaging associated neurodegenerationaging associated neurodegenerative diseaseaging relatedaging related neurodegenerationaging related neurodegenerative diseaseaging related neurodegenerative disorderalzheimer riskanosphrasiacase reportchronic effect of COVID-19chronic symptomco-morbidco-morbiditycohortcomorbiditycoronavirus diagnosiscoronavirus disease 2019coronavirus disease 2019 consequencecoronavirus disease 2019 diagnosiscoronavirus disease 2019 disease severitycoronavirus disease 2019 effectcoronavirus disease 2019 impactcoronavirus disease 2019 infected patientcoronavirus disease 2019 infectioncoronavirus disease 2019 negativecoronavirus disease 2019 patientcoronavirus disease 2019 positive patientcoronavirus disease 2019 severitycoronavirus disease 2019 testcoronavirus disease 2019 testscoronavirus disease 2019 viruscoronavirus disease diagnosiscoronavirus disease infected patientcoronavirus disease patientcoronavirus disease positive patientcoronavirus disease severitycoronavirus disease testcoronavirus disease testscoronavirus disease-19coronavirus disease-19 impactcoronavirus disease-19 patientcoronavirus disease-19 viruscoronavirus infectious disease-19coronavirus patientcoronavirus testcoronavirus testsdata resourcedata sharing networksdata sharing resourcedecline in functiondecline in functional statusdementia riskdemographicsdevelopmentaldiagnosed with COVIDdiagnosed with COVID-19diagnosed with COVID19diagnosed with SARS-CoV-2diagnosed with coronavirusdiagnosed with coronavirus 2019diagnosed with coronavirus diseasediagnosed with coronavirus disease 2019drug/agentelderly patientepidemiologicepidemiologicalfollowing COVID-19 infectionfollowing SARS-CoV-2 infectionfollowing SARS-CoV2 infectionfollowing infection by SARS-CoV-2following severe acute respiratory distress syndrome CoV-2 infectionfunctional declinefunctional status declinehCoV19head achehealth insurance for disabledhigh riskhistorieshost responsehuman old age (65+)immune system responseimmunoresponseimprovedinfected with COVID-19infected with COVID19infected with SARS-CoV-2infected with SARS-CoV2infected with coronavirus disease 2019infected with severe acute respiratory syndrome coronavirus 2innovateinnovationinnovativelate in lifelate lifelong-term consequence of severe acute respiratory distress syndrome-cov-2 infectionlong-term consequences of COVID-19long-term consequences of SARS-CoV-2 infectionlong-term consequences of coronavirus disease-19long-term effects of COVID-19long-term effects of coronavirus disease-19long-term health consequences of COVID-19long-term health consequences of SARS-CoV2 infectionlong-term impact of COVID-19long-term impact of SARS-CoV-2 infectionloss of smellmentalmental illnessmilitary veteranmobility aidmobility devicenCoV2neural degenerationneurocognitive outcomes of coronavirus disease-19neurocognitive symptoms and sequelae during COVID-19neurodegenerationneurodegenerativeneurological degenerationneurological diseaseneuronal degenerationneuropsychiatricneuropsychiatric diseaseneuropsychiatric disorderneuropsychiatric sequelae in COVID-19neuropsychiatric sequelae of COVID-19neuropsychiatric sequelae of SARS-CoV-2neuropsychiatric sequelae of coronavirus disease-19neuropsychiatrynursing homeolder adultolder adulthoodolder patientolfactory lossover 65 yearspandemic effectpandemic impactpandemic outcomepandemic repercussionspatient infected with COVIDpatient infected with COVID-19patient infected with SARS-CoV-2patient infected with coronavirus diseasepatient infected with coronavirus disease 2019patient infected with severe acute respiratory syndrome coronavirus 2patient with COVIDpatient with COVID-19patient with COVID19patient with SARS-CoV-2patient with coronavirus diseasepatient with coronavirus disease 2019patient with severe acute respiratory distress syndrome coronavirus 2persistent symptompost COVID cognitive impairmentpost SARS-CoV-2 infectionprevious COVID-19 infectionprevious SARS-CoV-2 infectionprevious SARS-CoV2 infectionprevious severe acute respiratory distress syndrome CoV-2 infectionprior COVID-19 infectionprior SARS-CoV-2 infectionprior SARS-CoV2 infectionprior severe acute respiratory distress syndrome CoV-2 infectionpsychiatric co-morbiditypsychiatric comorbiditypsychiatric illnesspsychiatric symptompsychological disorderracial diversityracially diverseresponserisk factor for dementiarisk for dementiascreeningscreeningssevere acute respiratory syndrome coronavirus 2 diagnosissevere acute respiratory syndrome coronavirus 2 disease severitysevere acute respiratory syndrome coronavirus 2 infected patientsevere acute respiratory syndrome coronavirus 2 negativesevere acute respiratory syndrome coronavirus 2 patientsevere acute respiratory syndrome coronavirus 2 positive patientsevere acute respiratory syndrome coronavirus 2 severitysevere acute respiratory syndrome coronavirus 2 testsevere acute respiratory syndrome coronavirus 2 testsstatistic methodssurvive COVID-19survive SARS-CoV-2test for COVIDvascularventilationveteran population≥65 years
Description preview
The psychological and social impact of the pandemic have been severe and likely will have significant mental effects over the long term. There is also emerging evidence that suggests that COVID-19 may have direct effects on the brain or trigger immune responses that have additional adverse consequences on brain function and mental health in…
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