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Locating the neural substrates for the flexor synergy after stroke

Organization UNIVERSITY OF NEWCASTLELocation NEWCASTLE UPON TYNE, UNITED KINGDOMPosted 15 Mar 2021Deadline 28 Feb 2026 ⚠️
NIHUS FederalResearch GrantFY2025AccelerationAddressAnatomic SitesAnatomic structuresAnatomyAnimalsAnteriorApoplexyAreaAutomobile DrivingBasal GangliaBasal NucleiBrainBrain Nervous SystemBrain Vascular AccidentCell BodyCellsCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCorticospinal TractsDataDeep Brain StimulationDevelopmentDiseaseDisorderDissociationDorsalDrug usageDrugsElbowElectrodesEncephalonExtremitiesFaceFlexorHandHealthHumanImpairmentImplantLaboratoriesLeadLearningLeftLesionLiftingLimb structureLimbsMacacaMacaqueMeasurementMeasuresMedicationMedulla SpinalisMembrum superiusMethodsModelingModern ManMonkeysMotorMotor CellMotor CortexMotor NeuronsMovementMuscleMuscle Cell ContractionMuscle ContractionMuscle TissueMuscular ContractionNatureNerve CellsNerve UnitNeural CellNeurocyteNeuronsNon-TrunkNucleus RuberOperative ProceduresOperative Surgical ProceduresParalysis AgitansParkinsonParkinson DiseasePathologicPathway interactionsPatientsPb elementPersonsPharmaceutical PreparationsPhysiatric ProcedurePhysical Medicine ProcedurePhysical TherapeuticsPhysical therapyPhysiologicPhysiologicalPhysiotherapyPrimary ParkinsonismPrimatesPrimates MammalsRecoveryRed NucleusRed nucleus structureReflexReflex actionReticular FormationShoulderSpeedSpinalSpinal CordStrokeSurgicalSurgical InterventionsSurgical ProcedureSyndromeSystemTask PerformancesTendon structureTendonsTennisTherapeutic InterventionTimeTorqueTrainingUpper ExtremityUpper LimbVideo RecordingVideorecordingWorkafter strokearmbody movementbrain attackcerebral vascular accidentcerebrovascular accidentdevelopmentaldexteritydisabilitydrivingdrug usedrug/agentexperimentexperimental researchexperimental studyexperimentsfacesfacialhandsheavy metal Pbheavy metal leadimprovedinstrumentintervention therapyischemic lesionkinematic modelkinematicsloss of functionmagnocellularmotoneuronmuscularneuralneural circuitneural circuitryneural stimulationneurocircuitryneuronalnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovelnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapypathwaypost strokepoststrokepreventpreventingprogramsspasticitystroke recoverystroke survivorstrokedstrokessurgerysynaptic circuitsynaptic circuitrysynergismvideo recording system

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Description preview

A stroke often damages motor areas of the brain. Understandably, this leads to a loss of movement
control: the limbs become weak, and movements are slower and less well-coordinated. In addition to loss of

function, patients also gain unwanted muscle contractions called synergies. For example, whenever the arm is

lifted (shoulder abduction), the…

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Locating the neural substrates for the flexor synergy after stroke β€” UNIVERSITY OF NEWCASTLE | UNITED KINGDOM | Mar 2021 | Dev Procure