grant

Leadership, Planning and Evaluation

Organization SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTELocation LA JOLLA, UNITED STATESPosted 1 May 1997Deadline 30 Apr 2027
NIHUS FederalResearch GrantFY2025AccreditationAnimal ModelAnimal Models and Related StudiesAreaAwardBasic Cancer ResearchBasic ResearchBasic ScienceBioinformaticsBiologyCCSGCancer CenterCancer Center Support GrantCancer TreatmentCancersCenter for Cancer ResearchCessation of lifeChemicalsDeathDedicationsDevelopmentDiseaseDisorderEducationEducation and TrainingEducational aspectsElementsEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEvaluationFacultyFundingFutureGEM modelGEMM modelGeneralized GrowthGenetically Engineered MouseGoalsGrantGrowthHospitalsHumanImmunologyImprove AccessIntermediary MetabolismInvestigatorsJointsLeadLeadershipMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMedicalMentorsMetabolic ProcessesMetabolismMissionModalityModern ManNCI Center for Cancer ResearchOutcomePb elementPilot ProjectsPreventionProcessR-Series Research ProjectsR01 MechanismR01 ProgramResearchResearch GrantsResearch PersonnelResearch Project GrantsResearch ProjectsResearch ResourcesResearchersResource SharingResourcesScienceSightStrategic PlanningSystemTechnologyTherapeuticTissue GrowthTrainingTraining and EducationTranslatingVisionaccreditedanti-cancer therapycancer therapycancer-directed therapydevelopmentalepigeneticallygenetically engineered mouse modelgenetically engineered murine modelheavy metal Pbheavy metal leadhuman tissuemalignancymeetingmeetingsmembermodel of animalmultidisciplinaryneoplasm/cancernew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapyontogenypilot studyprogramsrecruitsmall moleculestructural biologyvaccinologyvisual function
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Full Description

ABSTRACT – LEADERSHIP, PLANNING AND EVALUATION
The goal of the Sanford Burnham Prebys Medical Discovery Institute Cancer Center's planning process is to strategize and prioritize programmatic development, intra- and inter-programmatic activities, and Center-wide activities. Effective planning and evaluation processes enable the Center to fulfill its vision of making paradigm-shifting discoveries that will underlie novel therapeutic modalities by creating, translating, and disseminating exceptional cancer basic science. The Cancer Center has established a coordinated and multilayered planning and evaluation process. The de facto Cancer Center Executive Committee is the Cancer Center Leadership Team (CCLT) chaired by the Director and comprising the Deputy Director, the three Associate Directors (Administration, Shared Resources, and Training and Education), and the three Program Leaders, who provide scientific guidance, direction, and advice to the Director. The CCLT receives input from the Shared Resources Team, chaired by the Associate Director for Shared Resources, and the Administrative Team, chaired by the Associate Director for Administration. Advice on programmatic and thematic development, recruitment, and funding of pilot projects is solicited from the Cancer Center External Advisory Board (EAB) through an annual meeting and on an as-needed basis. Review shows that the goals of the 2014 Cancer Center 5-year Strategic Plan were fully achieved in terms of recruitment of seven new faculty in four defined growth areas (metabolism, epigenetics, immunology and bioinformatics), increased access to human tissues through arrangements with two local hospital systems, GEM models, and 21 translational pilot grant awards. A new five-year Strategic Plan was developed at a retreat attended by nearly all Center members in late November 2018, which established future scientific direction for the Programs and target areas for recruitment. The new Strategic Plan is a shared-governance document that combines bottom-up input from the Center faculty with elements of top-down planning by the Director and CCLT and is in concordance with the Institute's 10-year vision of building on existing strengths in research discovery (new targets) and early small-molecule lead discovery (therapeutics). The CCLT holds monthly meetings at which, among other activities, it evaluates the Center's progress in achieving goals established by the 5-year Strategic Plan, and in other areas, including education and team science. Future growth areas identified by the new Strategic Plan are for 13 recruitments in the next grant period in chemical biology, structural biology, bioinformatics, and immunology/vaccinology, while needed resources identified were improved access to animal models, new immunology targets, and the need to adapt more rapidly to developing technologies. Progress toward providing for these needs has already begun. Several recruitments are underway or planned for the coming year, in many cases as joint recruitments by two or more Programs.

Grant Number: 4P30CA030199-44
NIH Institute/Center: NIH

Principal Investigator: Paul Boutros

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