grant
IU Clinical Center: Drug Induced Liver Injury Network
Organization INDIANA UNIVERSITY INDIANAPOLISLocation INDIANAPOLIS, UNITED STATESPosted 30 Sept 2003Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY202521+ years oldActive Follow-upAddressAdultAdult HumanAgonistAlkaline PhosphataseAmbulatory Care FacilitiesAncillary StudyAnti-epilepticAttenuatedBactrimBile Duct ObstructionBiliary StasisBilirubinBilirubin IX alphaBiologicalBlood PlasmaBlood SerumBody TissuesCOVID-19 vaccinationCausalityCell BodyCellsCentrinCessation of lifeCholestasisChronicChronic Non-Suppurative Destructive CholangitisChronic Nonsuppurative Destructive CholangitisClinicalCotrimCounty HospitalsDataData Coordinating CenterData Coordination CenterDeathDevelopmentDouble-Blind MethodDouble-Blind StudyDouble-BlindedDouble-Masked MethodDouble-Masked StudyEGCGEGCG cpdElectronic Health RecordEligibilityEligibility DeterminationEnrollmentEpidemiologic ResearchEpidemiologic StudiesEpidemiological StudiesEpidemiologyEpidemiology ResearchEpigallocatechin GallateEslectinEtiologyFundingFunding OpportunitiesGWA studyGWASGastroenterologyGene variantGenesGeneticGoalsGreen Tea ExtractGreen Tea PolyphenolsHealthHealth CareHealth Care FacilityHealth FacilitiesHepatic CellsHepatic FailureHepatic Parenchymal CellHepatocyteHerbal dietary supplementHerbal supplementHospitalsImmunotherapeutic agentIndianaIndividualInfrastructureInjury to LiverInsozalinInterventionInvestigationInvestigatorsItchingKnowledgeLinkLiver CellsLiver FailureMacrobidMacrodantinMedical InformaticsMessenger RNAMethodologyMolecularMorbidityMorbidity - disease rateMultiple InjuriesMultiple TraumaNational Institutes of HealthNatural HistoryNitrofurantoinOutcomeOutpatient ClinicsPPAR alphaPPAR-αPPARalphaPPARαPathway interactionsPatient outcomePatient-Centered OutcomesPatient-Focused OutcomesPatientsPeroxisome Proliferator-Activated Receptor alphaPeroxisome Proliferator-Activated Receptor αPharmacogeneticsPhenotypePilot ProjectsPlacebo ControlPlacebosPlasmaPlasma SerumPrimary biliary cholangitisPrimary biliary cirrhosisPrivatizationProbabilityProspective StudiesProtocolProtocol ScreeningProtocols documentationPruritic DisorderPruritisPruritusPublicationsQOLQuality of lifeRNA SeqRNA sequencingRNAseqRandomizedRecoveryResearchResearch PersonnelResearchersReticuloendothelial System, Serum, PlasmaRetrospective StudiesRisk FactorsRisk-associated variantSARS-CoV-2 vaccinationSMZ-TMPSafetyScientific PublicationSerious Adverse EventSerumSevere Adverse EventSevere acute respiratory syndrome coronavirus 2 vaccinationSeveritiesSham TreatmentSourceStethoscopesTMP-SMXTea catechinTestingTherapeuticTherapeutic ResearchTissuesTotal BilirubinTransplantationTrimedinTrimethoprim-SulfamethoxazoleTrimezoleUnderrepresented Ethnic MinorityUnderrepresented MinorityUnited States National Institutes of HealthUniversitiesVariantVariationactive followupacute drug induced liver injuryacute drug induced liver toxicityacute liver injuryadulthoodalkaline phosphomonoesteraseallelic variantanti-epileptic agentsanti-epileptic drugsattenuateattenuatesbile obstructionbile occlusionbiologiccare facilitiescausationcell typecholestatic diseasescholestatic disordercholestatic liver diseasecholestatic liver disordercholestatic syndromeschronic hepatic diseasechronic hepatic disorderchronic liver diseasechronic liver disorderclinical applicabilityclinical applicationclinical centercohortcoronavirus disease 2019 vaccinationdata integrationdevelopmentaldiet supplementdietary supplementsdisease causationdrug induced hepatotoxicitydrug induced liver diseasedrug induced liver injuryelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordenrollepidemiologicepidemiologic investigationepidemiologicalepidemiology studyepigallocatechin-3-gallateethnic diversityethnically diverseexome sequencingexome-seqfollow upfollow-upfollowed upfollowupgenetic variantgenome wide associationgenome wide association scangenome wide association studygenomewide association scangenomewide association studygenomic variantglobal gene expressionglobal transcription profileglycerophosphatasehepatic damagehepatic injuryimmune drugsimmune-based therapeuticsimmunologic therapeuticsimmunotherapeuticsimmunotherapy agentimproveditch sensationlarge data setslarge datasetsliver damageliver injurymRNAmeetingmeetingsmortalitynovelnutritional supplementoperationoperationspathwaypatient oriented outcomespilot studyplacebo controlledpolytraumaprospectiveracial diversityracially diverserandomisationrandomizationrandomly assignedrecruitrisk allelerisk generisk genotyperisk locirisk locusrisk variantserious adverse experienceserious adverse reactionsham therapytertiary caretotal measurement Bilirubintranscriptometranscriptome sequencingtranscriptomic sequencingtransplantunder-representation of minoritiesunder-represented minorityunderrepresentation of minoritiesvaccinate against COVID-19vaccinate against SARS-CoV-2vaccinate against coronavirus disease 2019vaccinate against severe acute respiratory syndrome coronavirus 2vaccination against COVID-19vaccination against SARS-CoV-2vaccination against Severe acute respiratory syndrome coronavirus 2vaccination against coronavirus disease 2019whole genome association analysiswhole genome association study
Description preview
PROJECT SUMMARY/ABSTRACT
Established in 2003, the DILIN currently has 6 clinical centers and one data coordinating center and is recruiting
eligible patients with well-defined idiosyncratic DILI into two ongoing multicenter prospective studies. Indiana
University is one of the founding clinical centers and has robustly participated in all DILIN…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click