grant

Intestinal G protein-coupled receptors (GPCRs): characterising gut GPCR-signalling with potential to treat colitis

Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
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Free fatty acid receptors (FFARs) are GPCRs known to be expressed in enteroendocrine cells and therefore likely to be involved in nutrient- and microbial metabolite signaling in the mammalian GI tract. FFA1 and FFA4 are co-activated by long-chain fatty acids (LCFAs) while FFA2 and FFA3 are preferentially co-stimulated by microbial-derived short…

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Intestinal G protein-coupled receptors (GPCRs): characterising gut GPCR-signalling with potential to treat colitis — UKR | Dev Procure