grant
Integrative Predictors of Temporomandibular Degenerative Joint Disease
Organization UNIV OF NORTH CAROLINA CHAPEL HILLLocation CHAPEL HILL, UNITED STATESPosted 22 Dec 2025Deadline 31 May 2030
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldAI AugmentedAI algorithmAI assistedAI based modelAI drivenAI enhancedAI integratedAI language modelsAI modelAI poweredAI systemAccountingActive Follow-upAddressAdultAdult HumanAgeAlgorithmsArchitectureAreaArthritisArthroplastyArtificial IntelligenceArtificial Intelligence enhancedAugmented by AIAugmented by the AIAugmented with AIAugmented with the AIBack AcheBack PainBackacheBioinformaticsBiological MarkersBlindnessBlood SerumBone structureCalibrationCaringCenter for Translational Science ActivitiesCephalalgiaCephalgiaCephalodyniaChildChild YouthChildhoodChildren (0-21)ChronicChronic Childhood ArthritisClinicalClinical DataCollaborationsCommunitiesCommunity DentistryComputer ReasoningComputer Software DevelopmentComputer Software EngineeringComputer Vision SystemsComputerized Medical RecordCranial PainDataData AnalyticsData ScienceData SetData SourcesDegenerative ArthritisDegenerative polyarthritisDentalDetectionDiagnosisDifferential DiagnosisDiseaseDisease ProgressionDisorderDisparitiesDisparityEarly DiagnosisElectronic Medical RecordEngineering / ArchitectureEnsureEnvironmentEvaluationEyeEyeballFoundationsFutureGeneralized GrowthGrowthHEAL InitiativeHead PainHeadacheHealthHealth Care CostsHealth CostsHealth systemHelping End Addiction Long-termHelping to End Addiction Long-termHistoryImageInflammationInformation RetrievalInformation extractionInfrastructureInstitutionInterdisciplinary ResearchInterdisciplinary StudyInterventionJaw JointJoint Prosthesis ImplantationJointsJuvenile Chronic ArthritisJuvenile Chronic PolyarthritisJuvenile Rheumatoid ArthritisKnowledgeLearningLocationMR ImagingMR TomographyMRIMRIsMachine IntelligenceMachine LearningMagnetic Resonance ImagingMandibular jointMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMichiganMigraineMigraine HeadacheModelingMonitorMorphologyMultidisciplinary CollaborationMultidisciplinary ResearchMultimodal ImagingMusculoskeletalNIDCRNIDRNMR ImagingNMR TomographyNational Institute of Dental ResearchNational Institute of Dental and Craniofacial ResearchNational Institutes of HealthNatural Language ProcessingNorth CarolinaNuclear Magnetic Resonance ImagingOperative ProceduresOperative Surgical ProceduresOralOsteoarthritisOsteoarthrosisOutcomeOutcomes ResearchPainPainfulPatient CarePatient Care DeliveryPatient MonitoringPatientsPatternPediatric cohortPerformancePhasePhenotypePoliciesPositionPositioning AttributePrecision careProbabilistic ModelsProbability ModelsPrognosisProteinsProtocolProtocols documentationPublicationsRecording of previous eventsRelapseReplacement ArthroplastyResearchResource SharingRetreatmentRetrospective cohortRiskRisk FactorsRoleSalivaSamplingScientific PublicationSerumSeveritiesSoftware EngineeringSourceStatistical ModelsStrategic PlanningSurgicalSurgical InterventionsSurgical ProcedureSymptomsTMJTMJ DiseasesTMJ DisordersTMJDTechniquesTechnologyTemporomandibular DisordersTemporomandibular JointTemporomandibular Joint DiseasesTemporomandibular Joint DisordersTemporomandibular Joint and Muscle DisorderTestingTextTherapeutic InterventionTissue GrowthTrainingTransformer language modelTranslatingUnited States National Institutes of HealthUniversitiesValidationWorkWorld Health OrganizationZeugmatographyactive followupadulthoodadvanced analyticsagesanalyzing longitudinalarthriticartificial intelligence algorithmartificial intelligence assistedartificial intelligence augmentedartificial intelligence drivenartificial intelligence integratedartificial intelligence language modelsartificial intelligence modelartificial intelligence poweredartificial intelligence-based modelbio-markersbiologic markerbiomarkerbonecare for patientscare of patientscaring for patientschild patientsclinical careclinical decision-makingco-morbidco-morbiditycomorbiditycomputer visioncone-beam CTcone-beam computed tomographycraniofacialcraniofaciescustomized therapycustomized treatmentdata collected in real worlddata managementdata modalitiesdata sharingdegenerative joint diseasedepositorydiagnostic criteriadiagnostic tooldisease diagnosisdisease phenotypedisease prognosisdisease prognosticationdrug relapseearly detectionenhanced with AIenhanced with Artificial Intelligenceevidence baseexperiencefeature selectionfederated dataflexibilityflexiblefollow upfollow-upfollowed upfollowuphead achehealinghigh riskhistorieshypertrophic arthritisimage registrationimagingimprovedindividualized careindividualized medicineindividualized patient careindividualized patient treatmentindividualized therapeutic strategyindividualized therapyindividualized treatmentinflammation markerinflammatory markerinnovateinnovationinnovativeinsightintervention therapyjoint arthroplastyjoint damagejoint degenerationjoint degradationjoint destructionjoint injuryjoint replacementjoint tissue degenerationjoint traumajuvenile arthritisjuvenile idiopathic arthritiskidsknowledge baselarge language modellarge scale language modellongitudinal analysislongitudinal data setlongitudinal datasetmachine based learningmassive scale language modelsmobile appmobile applicationmobile device applicationmulti-modal datamulti-modal datasetsmulti-modal imagingmulti-modalitymulti-modality imagingmultimodal datamultimodal datasetsmultimodalitymultimodality imagingnatural language understandingnew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnovelnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetontogenyopen sourceoptimal therapiesoptimal treatmentspatient centeredpatient orientedpatient specific therapiespatient specific treatmentpediatricpediatric health outcomespediatric patientspersonalized carepersonalized patient carepractical implementationpragmatic implementationpreventpreventingprognosis modelprognostic modelprognostic toolprospectiveradiomicsre-treatmentreal world datarelapse predictionrepositorysearch engineskeletal structuresocial rolestatistical linear mixed modelsstatistical linear modelssubchondral bonesurgerytailored medical treatmenttailored therapytailored treatmenttargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttooltranslational research centertranslational sciences centertreatment strategyunique treatmentusabilityvalidationsvision lossvisual lossvolume CTvolume computed tomographyvolumetric computed tomographyyoungster
Description preview
ABSTRACT
Temporomandibular Disorders (TMDs) represent a significant burden on musculoskeletal health, accounting for an
estimated $4 billion in healthcare costs annually. Pediatric Temporomandibular Degenerative Joint Disease (TM DJD) is
especially concerning, with risks including growth abnormalities, severe joint damage, and potential…
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