grant
InHANCE: Imaging Innovation for Head And Neck Cancer Evaluation & Treatment Delivery
Organization UNIVERSITY OF TX MD ANDERSON CAN CTRLocation HOUSTON, UNITED STATESPosted 18 Aug 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY2025Adverse Late EffectsAfter CareAfter-TreatmentAftercareAnnual ReportsAsialiaAwardCaliberCancer SurvivorCancersCausalityCharacteristicsChemopreventionClinicalClinical TrialsComputer AnalysisDataDetectionDevelopmentDevicesDiagnosisDiseaseDisorderEpidemicEpidermoid CarcinomaEtiologyEvaluationFunctional ImagingFundingGeneralized GrowthGrantGrowthHNC patientHPVHPV caused cancerHPV driven cancersHPV induced cancerHPV malignancyHPV+ cancerHPV-Related MalignancyHPV-associated cancerHPV-associated malignancyHPV-related cancerHead and NeckHead and Neck CancerHead and Neck CarcinomaHead and neck structureHealth CareHuman Papilloma VirusHuman Papilloma Virus-Related MalignancyHuman Papilloma Virus-Related Malignant NeoplasmHuman Papilloma Virus-associated cancerHuman Papilloma Virus-associated malignancyHuman Papilloma Virus-related cancerHuman PapillomavirusHuman papillomavirus cancerHuman papillomavirus induced cancerHuman papillomavirus malignancyHuman papillomavirus-Related MalignancyHuman papillomavirus-Related Malignant NeoplasmHyposalivationImageImage AnalysesImage AnalysisImage-Guided SurgeryImaging ProceduresImaging TechnicsImaging TechniquesImpairmentIndividualInfectious Human Wart VirusInjuryInvestigatorsKnowledgeLate EffectsMalignant Head and Neck NeoplasmMalignant NeoplasmsMalignant TumorMeasuresMedical RehabilitationModificationMonitorMorbidityMorbidity - disease rateMouth DrynessMuscleMuscle TissueNormal TissueNormal tissue morphologyOperative ProceduresOperative Surgical ProceduresOsteoradionecrosisOutcomePatient riskPatientsPersonsPhysiologic ImagingPlanocellular CarcinomaPrevention therapyProbabilityPublic HealthQOLQOL improvementQuality of lifeRadiation OncologyRadiation therapyRadiotherapeuticsRadiotherapyRandomizedRehabilitationRehabilitation therapyReportingResearchResearch PersonnelResearch ResourcesResearchersResourcesRiskSalivary hypofunctionScientistSeasonsSelection for TreatmentsSeriesSquamous CarcinomaSquamous Cell EpitheliomaSquamous cell carcinomaStagingSurgicalSurgical InterventionsSurgical ProcedureSymptomsTherapeuticTherapeutic InterventionTherapy Clinical TrialsTimeTissue GrowthToxic effectToxicitiesTreatment EfficacyUnited StatesXerostomiaXerostomicacute toxicityanatomic imaginganatomical imagingaptyalismaspiratebiomedical imagingcausationcohortcomputational analysescomputational analysiscomputer analysescurative interventioncurative therapeuticcurative therapycurative treatmentsdeath riskdevelopmentaldisease causationdry mouthexperiencehead and neck cancer patienthead/neck cancerhuman papillomavirus associated malignancyhuman papillomavirus caused cancerhuman papillomavirus driven cancershuman papillomavirus-associated cancerhuman papillomavirus-related cancerimage evaluationimage guided interventionimage interpretationimage-based methodimagingimaging biomarkerimaging detectionimaging markerimaging methodimaging modalityimaging-based biological markerimaging-based biomarkerimaging-based detectionimaging-based disease detectionimaging-based markerimprovedimproved outcomeimprovements in QOLimprovements in quality of lifeindividual patientinjuriesinjury to tissueinnovateinnovationinnovativeintervention efficacyintervention therapyintra-operative imagingintraoperative imagingmalignancymalignant head and neck tumormortalitymortality riskmultidisciplinarymuscularneoplasm/cancernovelontogenyoral drynessphysiological imagingpost treatmentpreservationpreventpreventingprogramsquality of life improvementquantitative imagingradiation treatmentrandomisationrandomizationrandomly assignedrehab therapyrehabilitativerehabilitative therapyrisk stratificationsalivary gland hypofunctionselection of treatmentside effectstatistical learningstratify risksurgerysurgical imagingtherapeutic efficacytherapy efficacytherapy selectiontissue injurytreatment selectiontreatment with radiationtumorwart virus
Description preview
ABSTRACT: Overall
Head and neck cancer afflicts nearly 65,000 persons annually in the United States, with an explosive growth, in
what has now reached epidemic levels, human papilloma virus associated (HPV+) squamous carcinoma.
Advances in therapy and changes in etiology have resulted in long-term survival for the majority of head and
neck cancer…
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