grant
Infant diet and cardiometabolic risk among children born preterm
Organization BRIGHAM AND WOMEN'S HOSPITALLocation BOSTON, UNITED STATESPosted 23 Aug 2023Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY20250-11 years old2 year old2 years of age3rd trimester5 year old5 years of ageACRP30 proteinAccelerationActive Follow-upAddressAgeAmerican Heart AssociationBP reductionBiological MarkersBiometricsBiometryBiostatisticsBirthBlood SerumBrainBrain Nervous SystemBreast MilkBreastmilkC-reactive proteinCaloric IntakeCardiologyCardiometabolic DiseaseCardiometabolic DisorderChildChild YouthChildhoodChildren (0-21)ChronicClinicalClinical TrialsCollaborationsConceptionsD-GlucoseDataDeveloping fetusDevelopmentDevelopmental ProcessDextroseDiabetes MellitusDietDiscipline of obstetricsDiseaseDisorderEncephalonEndocrinologyEnergy IntakeEnsureExhibitsFatsFatty acid glycerol estersFetal DevelopmentFetusFortificationFutureGeneralized GrowthGestationGlucoseGoalsGrowthHealthHistoryHospital AdmissionHospitalizationHospitalsHuman MilkHuman Mother's MilkHumulin RHypertensionImpairmentIndividualInfantInsulinIntakeInterventionIntervention TrialInterventional trialLast TrimesterLeptinLifeLife course epidemiologyLifecourse epidemiologyLipidsMacronutrient IntakeMacronutrientsMacronutrients NutritionMalnutritionMammary Gland MilkMeasuresMetabolic syndromeMetabolism and EndocrinologyMonitorMorbidityMorbidity - disease rateMother's MilkNeonatal Intensive Care UnitsNeonatologyNeural DevelopmentNewborn Intensive Care UnitsNovolin RNutrientNutritional DeficiencyNutritional SupportOb Gene ProductOb ProteinObese Gene ProductObese ProteinObesityObstetricsOutcomeParticipantParturitionPatternPhysiologyPopulationPregnancyPremature InfantPreventiveProteinsProteins, specific or class, C-reactiveRandomized, Controlled TrialsRecommendationRecording of previous eventsRegular InsulinResearchRisk FactorsSerumSurvivorsTestingThird Pregnancy TrimesterThird TrimesterTissue GrowthUndernutritionVascular Hypertensive DiseaseVascular Hypertensive DisorderVisitVulnerable PopulationsWeight GainWeight IncreaseWorkactive followupadipocyte complement-related protein 30-kDaadipocyte, C1q and collagen domain containing proteinadiponectinadiposityadult youthage 2 yearsage 5 yearsaged 2 yearsaged two yearsagesapM-1 proteinapM1 (adipose-specific) proteinbio-markersbiologic markerbiomarkerblood pressure reductionbody weight gainbody weight increasecaloric dietary contentcardiometaboliccardiometabolic riskcardiometabolismcardiovascular healthclinical carecohortcorpulencedesigndesigningdevelopmentaldiabetesdietarydietary deficiencydietsearly childhoodexperienceextreme prematurityextremely premature infantextremely pretermextremely preterm infantfive year oldfive years of agefollow upfollow-upfollowed upfollowuphigh blood pressurehistorieshyperpiesiahyperpiesishypertensive diseasehypertensive disorderimprovedinfant nutritioninfant outcomeinfants born prematureinfants born prematurelyinnovateinnovationinnovativekidslater in lifelater lifelower BPlower blood pressurelowers blood pressuremacronutrient consumptionmalleable riskmalnourishedmaternal milkmeetingmeetingsmetabolism measurementmetabolomicsmetabonomicsmodifiable riskneonatal ICUneonatal careneurodevelopmentnutrition deficiencynutrition deficiency disordernutritional carenutritional deficiency disordernutritional therapyobesity riskobstetric careontogenypediatricpoint of carepostnatalpremature babypremature infant humanpreterm babypreterm infantpreterm infant humanprotein intakepublic health relevancerandomized control trialreduce BPreduce blood pressurereduction in BPreduction in blood pressurerisk for obesityrisk of obesitysite targeted deliverystandard of caretargeted deliverytheoriestwo year oldtwo years of agevery prematurevery pretermvulnerable groupvulnerable individualvulnerable peoplewt gainyoung adultyoung adult ageyoung adulthoodyoungster
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Project Summary / Abstract
Each year, over 63,000 U.S. infants are born very preterm, prior to 32 weeks of gestation. With >90% now
surviving to discharge due to better obstetrical and neonatal intensive care unit (NICU) management, the
present challenge is to reduce short- and long-term morbidities experienced by survivors, including the two- to…
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