🗂️
Archived grant — no longer open
This grant has closed and is kept as a historical reference. Browse current grants for active opportunities.
grant
In vivo Visualization of Delayed Wallerian Degeneration in Peripheral Nerve Injury
Organization WASHINGTON UNIVERSITYLocation SAINT LOUIS, UNITED STATESPosted 1 Apr 2024Deadline 31 Mar 2026 ⚠️
NIHUS FederalResearch GrantFY20252-photon3-D3-Dimensional3-Pyridinecarboxamide3DAddressAffectAnimalsArchitectureAxonBiologyBody TissuesCell Culture TechniquesCharacteristicsClinicalComplexDPN hydrolaseDPNaseDataDevelopmentDihydronicotinamide Adenine DinucleotideDiphosphopyridine NucleotidaseDiphosphopyridine NucleotideDistalEmotional StressEngineering / ArchitectureEsthesiaEventExtremitiesFLIM imagingFailureFluorescenceFutureGatekeepingGeneralized GrowthGeneticGoalsGrowthHourHumanImageImaging DeviceImaging InstrumentImaging ToolImplantIn VitroInjuryIntermediary MetabolismInvestigationLengthLibrariesLimb structureLimbsLinkLong-term painMaintenanceMeasurementMeasuresMetabolicMetabolic PathwayMetabolic ProcessesMetabolismMethodsMiceMice MammalsMicroscopyModalityModelingModern ManMolecularMolecular ProbesMonitorMorphologyMurineMusMuscleMuscle TissueMyoneural JunctionNAD+ GlycohydrolaseNAD+ NucleosidaseNADaseNadideNerveNerve DegenerationNerve RegenerationNerve TissueNervous TissueNeuro-regenerationNeuromuscular JunctionNeuron DegenerationNeuroregenerationNiacinamideNicotinamideNicotinamide MononucleotideNicotinamide adenine dinucleotideNicotinamide-Adenine DinucleotideNicotinamidumNicotinic acid amideNicotylamideNon-TrunkOperative ProceduresOperative Surgical ProceduresOptical reporterOpticsOrganOutcomePNS DiseasesPathway interactionsPatientsPellagra-Preventing FactorPeripheral Nerve DiseasesPeripheral Nervous SystemPeripheral Nervous System DiseasesPeripheral Nervous System DisordersPeripheral NeuropathyPeripheral nerve injuryPersistent painPersonsPositionPositioning AttributeProcessPrognosisRecoveryRegenerative capacityReporterReporter GenesReportingResolutionRodentRodentiaRodents MammalsRoleSensationSensorySiteSkinSterilitySurgicalSurgical InterventionsSurgical ProcedureSystemTherapeuticThinkingTimeTissue GrowthTissuesTransgenic MiceTransgenic OrganismsTraumatic Nerve InjuryTravelUnited StatesValidationVisualizationVitamin B 3Vitamin B3Vitamin PPWallerian DegenerationWorkaxon regenerationaxonal degenerationaxonal regenerationcell culturecell culturesconfocal imagingconstant paincyaninedegenerative axondevelopmentalexperimentexperimental researchexperimental studyexperimentsflexibilityflexiblefluorescence life-time imagingfluorescence life-time imaging microscopyfluorescence lifetime imagingfluorescence lifetime imaging microscopygatekeeperhigh resolution imagingimage-based methodimagingimaging approachimaging based approachimaging in vivoimaging methodimaging modalityimaging probeimaging systemimprovedimproved outcomein vivoin vivo Modelin vivo imaginginjuriesintra-vital imagingintravital imaginglasting painlongitudinal imagingmetabolic profilemigrationminimally invasivemuscularnerve injurynerve reconstructionnerve repairnerve transectionnervous system regenerationneuralneural degenerationneural injuryneural regenerationneurodegenerationneurodegenerativeneurological degenerationneuromuscularneuronal degenerationneuroregenerativenew approachesnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovelnovel approachesnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel strategiesnovel strategynovel therapeuticsnovel therapyon-going painongoing painontogenyoptic imagingopticaloptical imagingpathwayperipheral nerve crush injuriespharmacologicphysical disabilityphysically disabledphysically handicappedregenerated nerveregeneration abilityregeneration capacityrepairrepairedresolutionssciatic nervesciatic nerve injurysecondary degenerationsenescencesenescentserial imagingsmall moleculesocial rolespatial and temporalspatial temporalspatiotemporalsterilesurgerytemporal measurementtemporal resolutionthoughtsthree dimensionaltime intervaltime measurementtooltransgenictwo-photonvalidationsvirtual
Applications closed.
Description preview
SUMMARY
Peripheral nerve injuries are common and debilitating conditions affecting more than one hundred thousand
people annually in the United States. Prognosis for recovery of severe nerve injuries is poor, as high-grade
axonotmetic and neurotmetic injuries usually do not spontaneously recover. These injuries require surgical
intervention and if…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click