grant

Improving the analysis and use of contaminated immunoassays: from methods development to implementation

Organization COLUMBIA UNIVERSITY HEALTH SCIENCESLocation NEW YORK, UNITED STATESPosted 1 Sept 2024Deadline 30 Jun 2029
NIHUS FederalResearch GrantFY20250-11 years old3-D3-Dimensional3DAccountingAllergensAllergicAllergyAreaAssayAsthmaAttenuatedBayesian MethodBayesian MethodologyBayesian Statistical MethodBayesian approachesBayesian classification methodBayesian classification procedureBayesian posterior distributionBioassayBiologic SciencesBiological AgentBiological AssayBiological MarkersBiological ProductsBiological SciencesBioscienceBronchial AsthmaCalibrationChildChild YouthChildren (0-21)ClinicalClinical ResearchClinical StudyCollaborationsDataDiagnosisDiseaseDisorderDustELISAEcologic MonitoringEcological MonitoringEnvironmental MonitoringEnvironmental PollutionEnzyme-Linked Immunosorbent AssayEpidemiologic MethodologyEpidemiologic MethodsEpidemiologic ResearchEpidemiologic StudiesEpidemiologic research methodologyEpidemiologic research methodsEpidemiological MethodsEpidemiological StudiesEpidemiological TechniquesEpidemiologyEpidemiology ResearchGoalsGraphical interfaceHealthHealth SciencesImmunoassayInterventionInvestigatorsJointsLife SciencesMeasurementMeasuresMedicineMethodsMethods EpidemiologyMethods in epidemiologyModelingMorbidityMorbidity - disease rateNeighborhoodsNew York CityOutcomePaperProteinsProtocolProtocols documentationPublic HealthPythonsReactionReadingResearchResearch MethodologyResearch MethodsResearch PersonnelResearchersSamplingStatistical MethodsSystemTestingUncertaintyValidationantibody and antigen bindingasthmaticattenuateattenuatesbio-markersbiologic markerbiologicsbiomarkerbiopharmaceuticalbiotherapeutic agentclinical diagnosisclinical diagnosticsdetection limitdevelop softwaredeveloping computer softwaredoubtenvironmental contaminationenvironmental testingenzyme linked immunoassayepidemiologicepidemiologic investigationepidemiologicalepidemiology studygraphic user interfacegraphical user interfaceimprovedindoor allergenindoor concentrationsindoor levelsindoor measurementindoor valuesinsightkidsmedical diagnosticmethod developmentmodel buildingmultiplex assaynew technologynovel technologiesresearch and methodsresponsesoftware developmentsoftware user interfacestatistic methodsthree dimensionaltooluptakeuser-friendlyvalidationsyoungster
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PROJECT SUMMARY
Immunoassays – tests that estimate the concentration of analytes in a sample using antibody-antigen binding

reactions – are widely used for clinical diagnostics, biopharmaceutical analysis, and environmental monitoring.

The current method for estimating concentrations of analytes measured in immunoassays has several limitations,…

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Improving the analysis and use of contaminated immunoassays: from methods development to implementation — COLUMBIA UNIVE | Dev Procure