grant

Improving seated postural control and upper extremity function in bilateral CP with a robotic Trunk-Support-Trainer (TruST)

Organization COLUMBIA UNIV NEW YORK MORNINGSIDELocation NEW YORK, UNITED STATESPosted 1 Aug 2020Deadline 31 Jul 2026
NIHUS FederalResearch GrantFY20240-11 years oldAcquired brain injuryActivities of Daily LivingActivities of everyday lifeAddressAffectBilateralBrain InjuriesCNS plasticityCerebral PalsyChildChild YouthChildhoodChildren (0-21)ClassificationClinicDataEducationEducational aspectsEquilibriumEquipmentGoalsHeadHealthHomeImpairmentInterventionIntervention StrategiesLeisure ActivitiesLife ExpectancyMedical RehabilitationMembrum superiusMotorMovementMusculoskeletal EquilibriumNeuronal PlasticityPelvicPelvic RegionPelvisPlayPostural BalancePostural EquilibriumPostural adjustmentsPostural alterationsPostural changesPostureRehabilitationRehabilitation therapyResearchRoboticsSeriesSystemSystematicsTechnologyTherapeuticTrainingTreatment EfficacyUpper ExtremityUpper LimbVeinsWalkingWheel ChairsWheelchairsWorkarmbalancebalance functionbody movementbrain damagebrain-injuredcentral nervous system plasticityclinical practicecomparable efficacycomparative efficacycompare efficacycostdaily living functiondaily living functionalitydexterityeffective therapyeffective treatmentevidence basefunctional abilityfunctional capacityfunctional improvementfunctional independencehomesimprove functionimprovedimproved functional outcomesinnovateinnovationinnovativeintervention efficacyinterventional strategykidslocomotor learningmotor learningneural plasticityneuroplasticneuroplasticitynovelpediatricpostural controlrehab therapyrehabilitativerehabilitative therapyskillstechnological innovationtherapeutic efficacytherapy efficacyyoungster
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Full Description

Children with moderate to severe bilateral CP have poor upper extremity abilities and
segmental trunk control deficits. Their independent functional sitting is impaired with decreased

participation in leisure activities, education involvement. Therefore, promoting independent sitting

and improving postural and upper extremity abilities are critical to the health and functional

independence of children with moderate-to-severe bilateral CP (GMFCS III-IV). Despite

significant strides in upper extremity treatments of children with milder (unilateral) CP, there is

limited evidence supporting efficacy of treatments targeting seated postural control in bilateral

CP. Recent robotic equipment allows clinicians to address engagement, repetition, and intensity

to practice task-oriented movements in CP. In this vein, we postulate that robotics can offer a

unique platform to provide efficient motor learning-based training in children with bilateral CP by

implementing postural skill progression. Our team has developed a unique motorized Trunk-

Support-Trainer (TruST) to engage children in play-oriented practice with skill progression. TruST

creates a customized donut-like force field at the region of the torso where balance is lost to

provide active assistance beyond the sitting stability limits through a belt. The training is based

on principles of motor learning, including skill progression.

The overall goal of this work is to develop an evidence-based strategy to promote functional

independent sitting, maximize seated postural and upper extremity abilities, and improve sitting-

related ADLs. Our central hypothesis is that sitting and reaching benefits can be achieved when

a motor learning-based postural intervention is combined with postural-skill progression delivered

via TruST in comparison to a static trunk support. The innovation of this proposal, (RFA-HD-20-

005, ‘Pediatric Rehabilitation’) lies in the fusion of evidence-based clinical practice and novel

robotics with TruST. The result is a training paradigm where children with bilateral CP can receive

motor learning-based postural training in addition to postural skill progression that is tailored to

the child’s postural stability in sitting. If our hypotheses are supported, the TruST-intervention will

be a unique therapeutic solution for children with CP GMFCS III-IV to acquire and improve

independent functional sitting.

Grant Number: 5R01HD101903-05
NIH Institute/Center: NIH

Principal Investigator: Sunil Agrawal

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