grant

Improving Diabetes Health in Emerging Adulthood Through an Autonomy Supportive Intervention.

Organization WAYNE STATE UNIVERSITYLocation DETROIT, UNITED STATESPosted 6 Mar 2019Deadline 31 Jul 2026
NIHUS FederalResearch GrantFY202312-20 years old21+ years oldActive Follow-upAddressAdolescenceAdolescentAdolescent YouthAdultAdult HumanAfter CareAfter-TreatmentAftercareAgeBehaviorBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentBlood GlucoseBlood SugarBrittle Diabetes MellitusCaringChronicChronic DiseaseChronic IllnessClinicClinic VisitsClinical TrialsCommunicationCompetenceComplications of Diabetes MellitusConditioning TherapyDecision MakingDevelopmentDiabetes ComplicationsDiabetes MellitusDiabetes-Related ComplicationsDiabetic ComplicationsEngineeringExperimental DesignsFeedbackFeelingFrequenciesGlycohemoglobin AGlycosylated hemoglobin AGoalsHb A1Hb A1a+bHb A1cHbA1HbA1cHealthHealth Care ProvidersHealth PersonnelHealth behaviorHealth behavior changeHealthcareHealthcare ProvidersHealthcare workerHemoglobin A(1)IDDMInsulin-Dependent Diabetes MellitusInterventionIntervention StrategiesIntrinsic driveJuvenile-Onset Diabetes MellitusKetosis-Prone Diabetes MellitusKnowledgeLinkMeasuresMediatingMedicalMental DepressionMetabolic ControlModelingMoodsMotivationOutcomePatient Self-ReportPatientsPerceptionProcessProviderRandomizedResearchResearch DesignResearch ResourcesResourcesRiskRisk BehaviorsRisky BehaviorRoleSample SizeSelf DeterminationSelf DirectionSelf EfficacySelf ManagementSelf-ReportSiteSocial supportStudy TypeSudden-Onset Diabetes MellitusSystemT1 DMT1 diabetesT1DT1DMTarget PopulationsTestingText MessagingTimeTreatment EfficacyType 1 Diabetes MellitusType 1 diabetesType I Diabetes MellitusVisitYouthYouth 10-21active followupadolescence (12-20)adult youthadulthoodage groupagesat risk behaviorautomated text messageautomated textingbehavior changebehavior in diabetes managementbehavior interventionbehavior testbehavioral interventionbehavioral testcare providerschronic disorderclinical significanceclinically significantdepressiondesigndesigningdetermine efficacydevelopmentaldiabetesdiabetes behavioral managementdiabetes managementdiabetes self-carediabetes self-managementdiabetic managemente-HealtheHealthearly adulthoodeffectiveness trialefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationefficacy testingelectronic healthemerging adultemerging adulthoodempowermentevaluate efficacyexamine efficacyexperimentexperimental researchexperimental studyexperimentsextrinsic motivationfamily supportfeelingsfollow upfollow-upfollowed upfollowupglucometerglucose meterglucose monitorhealth carehealth care personnelhealth care workerhealth providerhealth related behaviorhealth workforcehealthcare personnelhemoglobin A1cimprovedindexinginnovateinnovationinnovativeinsulin dependent diabetesinsulin dependent type 1intervention designintervention effectintervention efficacyinterventional strategyintrinsic motivationjoint functionjuvenilejuvenile diabetesjuvenile diabetes mellitusjuvenile humanketosis prone diabetesmedical personnelmotivational enhancement therapymotivational interviewmulti-component interventionmulti-faceted interventionmulti-modal interventionmulticomponent interventionmultifaceted interventionmultimodal interventionmultiphase optimization strategyparticipant engagementpatient engagementpeer supportpoor health outcomepost treatmentprematureprematurityprimary outcomepsychologicpsychologicalrandomisationrandomizationrandomized, clinical trialsrandomly assignedreduced health outcomesatisfactionsexshort message serviceskillssocial rolesocial support networkstudy designtextingtheoriestherapeutic efficacytherapy designtherapy efficacytooltreatment designtreatment providertype I diabetestype one diabetesworse health outcomeyoung adultyoung adulthood
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Full Description

Project Summary
This project will use the multiphase optimization strategy (MOST) approach to test the efficacy of an autonomy

supportive behavioral intervention to improve metabolic control among older adolescents and emerging adults

(16-25) with T1D. Youth this age demonstrate chronic poor metabolic control that persists into adulthood

leading to the premature emergence of short- and long-term diabetes complications. Developmentally,

adolescence and emerging adulthood is a time when the need for independence and autonomy are particularly

salient. This new intervention will leverage youths’ desire for autonomy by designing an intervention to

support diabetes self-management autonomy. This intervention is guided by self-determination theory (SDT)

which suggests that autonomous (i.e., self-initiated, driven by intrinsic versus extrinsic motivation) diabetes

management depends upon three conditions: 1) the perception that one’s behavior is self-directed, 2) feelings

of competence, or self-efficacy, and 3) the existence of caring relationships supportive of the behavior. We have

identified three intervention components that target the SDT constructs. A question prompt list (QPL) is a

simple, inexpensive tool comprised of a list of questions that patients might consider asking their health care

provider during a clinic visit. QPLs empower patients to assume a more active role (asking questions and

stating concerns) during clinic visits. The Motivation Enhancing System (MES) is an eHealth intervention to

increase intrinsic motivation for health behavior change. MES content is based on the Motivational

Interviewing (MI) framework and the Information-Motivation-Behavioral Skills (IMB) model of health

behavior change which posits that behavior change results from the joint function of three critical components:

accurate information about risk behaviors or their replacement health behaviors, motivation to change

behavior, and behavioral skills necessary to perform the behavior (self-efficacy). Text message reminders

(TXT) are a strategy to encourage youth to complete their diabetes self-care that also lead to gains in self-

efficacy and a stronger relationship with diabetes care providers through greater communication and

satisfaction. We will test the efficacy of these intervention components toward improving metabolic control in a

component selection experiment (N=320). The experiment will use a factorial research design with random

assignment to determine which intervention components contribute to a clinically significant improvement

(≥0.5%) in HbA1c. The result of this research will be an optimized, multi-component intervention with effect

size estimates that will be used to inform a large scale, fully powered effectiveness trial. This theory-driven

intervention will be scalable to a variety of chronic illness contexts and the knowledge gained from this

research will inform self-determination theory and behavioral interventions targeting this population (for

which there currently are none).

Grant Number: 5R01DK116901-05
NIH Institute/Center: NIH

Principal Investigator: April Carcone

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