grant
Improved 3D EPI for Pre-Surgical Mapping of Epilepsy
Organization BOSTON CHILDREN'S HOSPITALLocation BOSTON, UNITED STATESPosted 10 Jul 2024Deadline 31 May 2029
NIHUS FederalResearch GrantFY20250-11 years old3-D3-Dimensional3DAD/HDADHDAbscissionAddressAffectAnti-epilepticArtifactsAttention deficit hyperactivity disorderBrainBrain Nervous SystemBrain regionCardiacCell Communication and SignalingCell SignalingChildChild YouthChildren (0-21)ClinicalCompensationComplexDataDrug resistanceEcho-Planar ImagingEcho-Planar Magnetic Resonance ImagingEchoplanar ImagingEchoplanar Magnetic Resonance ImagingEncephalonEpilepsyEpileptic SeizuresEpilepticsExcisionExtirpationFreedomFunctional MRIFunctional Magnetic Resonance ImagingGoalsHeadHead MovementsHistoryImageIntracellular Communication and SignalingLanguageLesionLibertyMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMapsMeasurementMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceModalityModelingMorphologic artifactsMotionMotor SkillsNMR ImagingNMR TomographyNational Institutes of HealthNeurosurgeonNoiseNuclear Magnetic Resonance ImagingOperative ProceduresOperative Surgical ProceduresPatientsPatternPhysiologicPhysiologicalPlanar Medical ImagingPopulationPositionPositioning AttributePredispositionPredominantly Hyperactive-Impulsive Type Attention-Deficit DisorderPredominantly Hyperactive-Impulsive Type Hyperactivity DisorderRecommendationRecording of previous eventsRemovalResearchResolutionRespirationScanningScheduleSeizure DisorderSeizuresSignal TransductionSignal Transduction SystemsSignalingSliceSurgicalSurgical InterventionsSurgical ProcedureSurgical RemovalSusceptibilityTechnologyTimeUnited States National Institutes of HealthUpdateVariantVariationZeugmatographyanti-epileptic agentsanti-epileptic drugsautistic childrenbiological signal transductionblood oxygen level dependentblood oxygenation level dependentbrain tissuechild patientschildhood epilepsychildren on the autism spectrumchildren with ASDchildren with autismchildren with autism spectrum disordercohortdrug resistanteffective therapyeffective treatmentepilepsiaepilepsy participantepilepsy patientepilepsy subjectepilepsy volunteerepileptic patientepileptic subjectepileptogenicfMRIfMRI scanflexibilityflexiblefunctional MRI scanfunctional lossfunctional magnetic resonance imaging scanhistoriesimage-based methodimagingimaging methodimaging modalityimprovedinnovateinnovationinnovativekidsmagnetic fieldmotor abilityneuro-surgeonnew technologynovelnovel technologiespatient populationpatients with epilepsypediatric epilepsypediatric patientspreservationpreventpreventingprospectiverecruitresearch studyresectionresistance to Drugresistant to Drugresolutionsrespiratory mechanismsimulationspatial and temporalspatial temporalspatial temporal imagingspatial temporal mappingspatiotemporalspatiotemporal imagingspatiotemporal mappingsuccesssurgerytheoriesthree dimensionaltoolvolunteeryoungster
Description preview
Project Summary
In pediatric epilepsy patients with drug-resistant seizures, surgical resection is the most effective treatment
option. The goal of resective surgery is to maximize removal of epileptic foci to attain seizure-freedom while
minimizing damage to surrounding brain regions to avoid permanent post-surgical functional loss. Functional…
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