grant
Identifying Residual Connectivity in Veterans with Spinal Cord Injury for Precision Neurorehabilitation
Organization VA NORTHERN CALIFORNIA HEALTH CARE SYSLocation MATHER, UNITED STATESPosted 1 Apr 2026Deadline 31 Mar 2031
VANIHUS FederalResearch GrantFY202621+ years oldActivities of Daily LivingActivities of everyday lifeAddressAdultAdult HumanAffectAnatomic SitesAnatomic structuresAnatomyAutonomic DysfunctionBiomedical EngineeringCNS plasticityCaringCase StudyCase-Base StudiesCell Communication and SignalingCell SignalingCervical InjuryCervical spinal cord injuryChronicClassificationClinicalClinical TreatmentClinical TrialsCommunitiesCompensationContralateralDataDevelopmentDevelopment PlansDiagnosisDisciplineDiseaseDisorderE-stimElectric StimulationElectromyographyEligibilityEligibility DeterminationEnrollmentEnvironmentEsthesiaFeedbackFiberFoundationsFunctional Residual CapacityFundingFutureGoalsHeterogeneityIndividualInjuryInternationalIntracellular Communication and SignalingInvestigatorsIpsilateralKnowledgeLesionLocomotionLower ExtremityLower LimbMeasurementMeasuresMedulla SpinalisMembrum inferiusMembrum superiusMentorsMethodologyMotorMotor Evoked PotentialsMotor outputMovementNervous System InjuriesNervous System TraumaNervous System damageNeuro rehabilitationNeurologicNeurologic DysfunctionsNeurologicalNeurological DamageNeurological InjuryNeurological traumaNeuronal DysfunctionNeuronal PlasticityNeurorehabilitationOutcomePainPainfulPalsyParalysedParticipantPatientsPersonalized medical approachPersonsPhysiciansPhysiologicPhysiologicalPhysiologyPlegiaPopulationProspective cohortProtocolProtocol ScreeningProtocols documentationQOLQOL improvementQuadriplegiaQuadriplegicQualitative ResearchQuality of lifeRecovery of FunctionReportingResearchResearch MethodologyResearch MethodsResearch PersonnelResearch PriorityResearch ProposalsResearchersResidualResidual stateSample SizeSensationSensorimotor functionsSensorySeveritiesSignal TransductionSignal Transduction SystemsSignalingSomatosensory Evoked PotentialsSpinalSpinal CordSpinal Cord TraumaSpinal TraumaSpinal cord injuredSpinal cord injurySurvey InstrumentSurveysSystematicsTechniquesTechnologyTestingTetraplegiaTrainingTranscranial magnetic stimulationTranslatingTranslationsTraumatic MyelopathyUpper ExtremityUpper LimbVeteransWorkadulthoodbarrier to carebarrier to health carebarrier to treatmentbio-engineeredbio-engineersbioengineeringbiological engineeringbiological signal transductionbody movementcareercareer developmentcase reportcentral nervous system plasticityclinical interventionclinical practiceclinical therapycohortdaily living functiondaily living functionalitydesigndesigningdevelopmentaldiagnostic criteriaelectrostimulationenrollexperimentexperimental researchexperimental studyexperimentsfirst in manfirst-in-humanfunctional abilityfunctional capacityfunctional improvementfunctional outcomesfunctional recoveryfunctional restorationimprove functionimprovedimproved functional outcomesimprovements in QOLimprovements in quality of lifeindividualized approachinjuriesinnovateinnovationinnovativeinsightkinematic modelkinematicsmotor controlmulti-modalitymultimodalityneuralneural circuitneural circuitryneural controlneural dysfunctionneural imagingneural plasticityneural regulationneuro-imagingneurocircuitryneuroimagingneurological dysfunctionneurological imagingneurological rehabneurological rehabilitationneuromodulationneuromodulatoryneurophysiologicalneurophysiologyneuroplasticneuroplasticityneuroregulationneurorehabneurorehabilitativeneurotechnologyneurotraumanew approachesnext generationnovelnovel approachesnovel strategiesnovel strategyobstacle to careobstacle to health careparalysisparalyticpersonalized approachpost-doctoral trainingprecision approachquality of life improvementrecruitresearch and methodsresearch studyrestore functionrestore functionalityrestore lost functionside effectsynaptic circuitsynaptic circuitrytailored approachtetraplegictranslationtrial regimentrial treatment
Description preview
Significance to VA: Spinal cord injury (SCI) is a devastating disease that results in permanent motor, sensory,
and autonomic dysfunction below the SCI lesion. However, recent clinical spinal neuromodulation research using
epidural electrical stimulation (EES) and transcutaneous spinal stimulation (TSS) has shown promise in restoring
voluntary…
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