Identifying novel DNA repair mechanisms during meiosis

DNA double-strand breaks (DSBs), where both strands of the DNA helix are broken at the same locus, are the most dangerous lesion to occur to the genome. DSBs must be repaired correctly and in a timely manner to ensure genomic stability. Two main mechanisms for DSB repair exist: non-homologous end-joining, whereby the ends of the DSB are cleaned up…