grant
Identifying Multi-Level Predictors and Outcomes of Oral Anticancer Medication Adherence Initiation and Persistence among Patients with Hematologic Malignancies
Organization UNIVERSITY OF PITTSBURGH AT PITTSBURGHLocation PITTSBURGH, UNITED STATESPosted 1 Aug 2024Deadline 31 Jul 2029
NIHUS FederalResearch GrantFY2025AccountingAdherenceAffectAfrican AmericanAfro AmericanAfroamericanB-Cell CLLB-Cell Chronic Lymphocytic LeukemiaB-Cell Chronic Lymphogenous LeukemiaB-Cell Chronic Lymphoid LeukemiaB-Cell Lymphocytic LeukemiaB-Lymphocytic LeukemiaBlackBlack raceCancer TreatmentCancersCaringCharacteristicsChronic B-Lymphocytic LeukemiaChronic Granulocytic LeukemiaChronic Lymphatic LeukemiaChronic Lymphoblastic LeukemiaChronic Lymphocytic LeukemiaChronic Lymphogenous LeukemiaChronic Myelocytic LeukemiaChronic Myelogenous LeukemiaChronic Myeloid LeukemiaClinicalDataDevelopmentDoseDropsDrug PrescribingDrug PrescriptionsDrugsEmploymentEthnic OriginEthnicityFutureGoalsHealthHealth Care UtilizationHematologic CancerHematologic MalignanciesHematologic NeoplasmsHematological MalignanciesHematological NeoplasmsHematological TumorHematopoietic CancerHematopoietic Cell TumorHematopoietic MalignanciesHematopoietic NeoplasmsHematopoietic Neoplasms including LymphomasHematopoietic TumorHematopoietic and Lymphoid Cell NeoplasmHematopoietic and Lymphoid NeoplasmsHispanicIndividualInfrastructureInsuranceInterventionInterviewInvestigatorsKnowledgeLifeMalignant Hematologic NeoplasmMalignant Hematopoietic NeoplasmMalignant Neoplasm TherapyMalignant Neoplasm TreatmentMalignant NeoplasmsMalignant TumorMeasuresMedicationMethodsMolecularMultiple MyelomaNon-HispanicNonhispanicNot Hispanic or LatinoOralOral CharactersOral ExaminationOutcomeParticipantPatient Self-ReportPatientsPatternPharmaceutical PreparationsPharmaciesPharmacy facilityPhasePlasma-Cell MyelomaPopulationProgression-Free SurvivalsQOLQuality of lifeRaceRacesReportingResearch MethodologyResearch MethodsResearch PersonnelResearchersRiskSamplingSelf-ReportSpecialtyStructureSymptom BurdenSymptomsSystemTimeWorkanti-canceranti-cancer therapyblood cancercancer of bloodcancer of the bloodcancer therapycancer typecancer-directed therapychronic lymphoid leukemiaclinical predictorsclinical relevanceclinically relevantcostdesigndesigningdevelop therapydevelopmentaldrug adherencedrug compliancedrug/agentexperiencehealth care service usehealth care service utilizationimprovedintervention developmentmalignancymedical specialtiesmedication adherencemedication administrationmedication compliancemedication non-adherencemedication nonadherencemedication prescriptionmortalitymyelomamyelomatosisneoplasm/cancerpillpoor health outcomeprescribed medicationprospectiveracialracial backgroundracial originreduced health outcomeresearch and methodsresponseresponse to therapyresponse to treatmentsocio-economicsocio-economicallysocioeconomicallysocioeconomicsstandard of caretherapeutic responsetherapy developmenttherapy responsetreatment developmenttreatment responsetreatment responsivenessworse health outcome
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Oral anticancer medications (OAM) are becoming standard of care for growing numbers of patients. Multiple myeloma (MM), chronic myeloid leukemia (CML), and chronic lymphocytic leukemia (CLL) are hematologic malignancies for which costly, long-term OAMs are a life-extending therapy. However, OAM nonadherence (i.e., delaying, not starting, taking…
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