🗂️
Archived grant — no longer open
This grant has closed and is kept as a historical reference. Browse current grants for active opportunities.
grant
How S. aureus protein SSL11 inhibits neutrophil migration
Organization LOUISIANA STATE UNIV A&M COL BATON ROUGELocation BATON ROUGE, UNITED STATESPosted 2 Jan 2019Deadline 31 Jul 2025 ⚠️
NIHUS FederalResearch GrantFY2025Adhesion MoleculeAdhesionsAffectAntibiotic ResistanceAntigen-Antibody ComplexAsthmaB cell differentiation factorB cell stimulating factor 2B-Cell Differentiation FactorB-Cell Differentiation Factor-2B-Cell Stimulatory Factor-2BCDFBSF-2BSF2Bacterial ToxinsBindingBinding SitesBiologyBlocking AntibodiesBlood NeutrophilBlood Polymorphonuclear NeutrophilBody TissuesBronchial AsthmaBronchoalveolar Lavage FluidCOBRECRISPRCRISPR/Cas systemCSF3CSF3 geneCausalityCell AdhesionCell Adhesion Molecule GeneCell Adhesion MoleculesCell LineCell LocomotionCell MigrationCell MovementCell modelCell surfaceCellLineCellular AdhesionCellular MigrationCellular MotilityCellular biologyCellular modelCenter of Biomedical Research ExcellenceCenters of Research ExcellenceClustered Regularly Interspaced Short Palindromic RepeatsCombining SiteDNA Molecular BiologyDataDeath RateDedicationsDiseaseDisorderEnvironmentEquilibriumEtiologyFamily memberFosteringG-CSFGCSFGenus staphylococcusGlycansGoalsGrippeH1N1H1N1 VirusHL-60 CellsHL60 CellsHPGFHepatocyte-Stimulating FactorHost DefenseHumanHybridoma Growth FactorIFN-beta 2IFNB2IL-6IL6 ProteinImmune ComplexImmune EvasionImmune systemIndividualInfectionInflammatoryInfluenzaInfluenza A Virus, H1N1 SubtypeInhalationInhalingIntegrinsIntegrins Extracellular MatrixIntensive CareIntensive Care UnitsInterleukin-6InvadedKnock-outKnockoutLipidsLungLung Respiratory SystemLung infectionsMGC45931MGI-2Marrow NeutrophilMediatingMetabolic GlycosylationMiceMice MammalsModern ManMolecularMolecular BiologyMolecular ConfigurationMolecular ConformationMolecular DiseaseMolecular InteractionMolecular StereochemistryMotilityMurineMusMyeloid Differentiation-Inducing ProteinNeutrophil InfiltrationNeutrophil RecruitmentNeutrophilic GranulocyteNeutrophilic InfiltrateNeutrophilic LeukocyteNull CellsNull LymphocytesPathogenesisPathogenicityPatientsPhasePlasmacytoma Growth FactorPneumoniaPolymorphonuclear CellPolymorphonuclear LeukocytesPolymorphonuclear NeutrophilsPolysaccharidesPrevalenceProtein FamilyProteinsReactive SiteRecombinantsReportingResistance to antibioticsResistant to antibioticsRestS aureusS. aureusS. aureus infectionSignaling MoleculeStaph aureusStaph aureus infectionStaphylococcal InfectionsStaphylococcusStaphylococcus aureusStaphylococcus aureus infectionStaphylococcus infectionStrains Cell LinesSuperantigensSystemTestingTissuesToxinUnited StatesVaccinesantibiotic drug resistanceantibiotic resistantbalancebalance functioncausationcell adhesion proteincell biologycell motilityclinical riskconformationconformationalconformational stateconformationallyconformationscultured cell linecytokinedefined contributiondesigndesigningdisease causationflu virus pandemicglycosylationhigh riskhost colonizationimmune evasiveimmunopathologyin vitro activityin vivoinfected with S. aureusinfected with Staph aureusinfected with Staphylococcus aureusinfluenza virus pandemicinhibiting antibodyinsightinterferon beta 2migrationmortality ratemortality ratiomouse modelmurine modelneutrophilnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapyopportunistic pathogenpandemic flupandemic influenzapandemic strain of influenzapathogenpneumonia modelpneumonia modelspneumonia therapypneumonia treatmentpulmonarypulmonary infectionssialyl Lewis asialyl Lewis xsialyl-Lexstaph infectionstreat pneumoniaventilator-acquired pneumoniaventilator-associated pneumonia
Applications closed.
Description preview
SUMMARY
S. aureus-associated pneumonia accounts for an estimated 50,000 staphylococcal infections per
year in the United States. S. aureus is one of the leading etiologic agents of ventilator-
associated pneumonia in the intensive care environment. S. aureus pneumonia has a high rate
of mortality due to the prevalence of antibiotic resistance…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click