How does the apicomplexan dynein complex mediate transport of micronemes in malaria parasite P. falciparum?
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Abstract
Plasmodium falciparum is the apicomplexan parasite responsible for the most severe form of human malaria. Parasitic invasion of host cells requires precise positioning of two organelles: the rhoptries and the micronemes. Microneme positioning is thought to be driven by the motor protein dynein and the adaptor complex FHF. Neither complex…
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