grant
High-throughput and Machine Learning Optimization of Fluorescent Sensors for Multiplexed Imaging in vivo
Organization UNIVERSITY OF WASHINGTONLocation SEATTLE, UNITED STATESPosted 9 Mar 2026Deadline 31 Dec 2030
NIHUS FederalResearch GrantFY20263-photon microscopy5-HT5-Hydroxytryptamine5HTAccelerationAddressAffectAffinityArtifactsAssayAxonBRAIN initiativeBehavioralBenchmarkingBest Practice AnalysisBioassayBiological AssayBody TissuesBrainBrain Nervous SystemBrain Research through Advancing Innovative Neurotechnologies initiativeBrain regionCalciumCell BodyCell Communication and SignalingCell SignalingCellsCephalicCollectionColorCommon Rat StrainsComplexCoupledCranialDNA mutationDataData BasesData SetDatabasesDetectionDevelopmentDimensionsDiseaseDisorderDopamineDrug ScreeningEncephalonEngineeringEnsureEnteramineFiberFutureG Protein-Complex ReceptorG Protein-Coupled Receptor GenesG-Protein-Coupled ReceptorsGPCRGenerationsGenetic ChangeGenetic defectGenetic mutationGenotypeGoalsHigh Throughput AssayHippophaineHourHydroxytyramineImageIntracellular Communication and SignalingInvestigatorsKineticsLaboratoriesLibrariesLigand BindingLightLinkLocationMachine LearningMeasuresMethodsMiceMice MammalsModernizationMolecularMolecular ProbesMonitorMorphologic artifactsMurineMusMutationNational Institutes of HealthNerve CellsNerve Impulse TransmissionNerve TransmissionNerve UnitNervous System DiseasesNervous System DisorderNeural CellNeurocyteNeurologic DisordersNeurological DisordersNeuromodulatorNeuronal TransmissionNeuronsNeurosciencesNeurosciences ResearchNoisePattern RecognitionPerformancePhenotypePhotobleachingPhotometryPhotonsPhotoradiationPropertyProteinsRatRats MammalsRattusResearchResearch PersonnelResearch ResourcesResearchersResourcesSerotoninSignal TransductionSignal Transduction SystemsSignalingSomatosensory CortexSpeedSystemTechnologyTestingTimeTissuesTrainingUnited States National Institutes of HealthValidationVariantVariationVisual Cortexawakeaxon signalingaxon-glial signalingaxonal signalingbenchmarkbiological signal transductioncalcium indicatordata basedevelopmentalgenome mutationglia signalingglial signalinghigh throughput screeningimagingimaging in vivoimprovedin vivoin vivo imagingindexinginnovateinnovationinnovativeinnovative neurotechnologieslenslensesmachine based learningmachine learning based modelmachine learning based prediction modelmachine learning based predictive modelmachine learning modelmachine learning predictionmachine learning prediction modelmolecular scalemultiphoton excitation microscopymultiphoton microscopymultiplexed imagingnerve signalingneuralneural imagingneural signalingneuro-imagingneuroimagingneurological diseaseneurological imagingneuronalneuronal signalingneurotechnologyneurotransmissionnew approachesnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynovelnovel approachesnovel strategiesnovel strategynovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachoptogeneticsscreeningscreeningssensorsomesthetic sensory cortexsuccesstechnology platformtechnology systemthree photon microscopytooltool developmentvalidationsvisual cortical
Description preview
PROJECT SUMMARY / ABSTRACT
Monitoring neuronal activity modulation is pivotal for elucidating brain functionality and addressing
neurological disorders. Despite the advancements brought by green fluorescent calcium indicators like
GCaMP and neuromodulator sensors, a considerable gap persists in the development of red fluorescent sensors
that…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click