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Heterogeneous Genetic Architecture in Lung Cancer Risk

Organization UNIVERSITY OF NEW MEXICO HEALTH SCIS CTRLocation ALBUQUERQUE, UNITED STATESPosted 9 Dec 2024Deadline 31 Jan 2026 ⚠️
NIHUS FederalResearch GrantFY20251st degree relativeAddressAffectAfrican American groupAfrican American individualAfrican American peopleAfrican American populationAfrican AmericansAfrican ancestryAfrican descentAllelesAllelomorphsBiologicalCancer CauseCancer EtiologyCandidate Disease GeneCandidate GeneCausalityCell Communication and SignalingCell SignalingCharacteristicsComplexDataDevelopmentDiseaseDisorderEnvironmentEnvironmental ExposureEpidemiologic ResearchEpidemiologic StudiesEpidemiological StudiesEpidemiology ResearchEtiologyEuropeanEuropean ancestryEventFamilyFamily Cancer HistoryFamily Medical HistoryFamily Medical History EpidemiologyFamily history ofFirst Degree RelativeFrequenciesGWA studyGWASGene variantGenesGeneticGenetic DeterminismGenetic StructuresGenetic predisposing factorGenotypeGerm LinesHabitsHealthHealth BenefitHereditaryHeritabilityHistoryIndividualInflammationInheritedIntracellular Communication and SignalingInvestigationJointsKnowledgeLinkLungLung Respiratory SystemMachine LearningMalignant Tumor of the LungMalignant neoplasm of lungMapsMethodsModelingMolecularNetwork AnalysisNicotine DependencePathway AnalysisPhenotypePopulationPredispositionPredisposition genePreventionPublic HealthPulmonary CancerPulmonary malignant NeoplasmRecording of previous eventsResearchResearch ResourcesResourcesRiskRisk FactorsRoleSignal TransductionSignal Transduction SystemsSignalingSmokingSmoking BehaviorSourceSubgroupSusceptibilitySusceptibility GeneTreesVariantVariationallelic variantbiologicbiological signal transductioncancer riskcase controlcase-controlledcausationcigarette smokingcigarette usedepositorydevelopmentaldisease causationepidemiologic investigationepidemiology studyfamily influencegene interactiongene locusgene signaturesgenetic analysisgenetic architecturegenetic determinantgenetic epidemiologic studygenetic epidemiologygenetic locusgenetic risk factorgenetic signaturegenetic variantgenome wide associationgenome wide association scangenome wide association studygenomewide association scangenomewide association studygenomic datagenomic datasetgenomic locationgenomic locusgenomic varianthigh riskhistoriesimprovedinherited factorinsightlarge data setslarge datasetslow-frequency mutationlung cancermachine based learningmachine learned algorithmmachine learning algorithmmachine learning based algorithmnew approachesnicotine addictionnicotine dependentnovel approachesnovel strategiesnovel strategyphenotypic datapredisposing generare allelerare mutationrare variantrepositoryscreeningscreeningssocial rolesusceptibility allelesusceptibility locussusceptibility variantwhole genome association analysiswhole genome association study

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Title: Heterogeneous genetic architecture in lung cancer risk
Project Summary/Abstract
Lung cancer is a multifactorial disease driven by environmental exposures, inherited germline genetic
variants, and an accumulation of somatic genetic events. Most lung cancer cases are attributed to cigarette
smoking. Approximately 10% of lung cancer cases…

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Heterogeneous Genetic Architecture in Lung Cancer Risk — UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR | UNITED STATES | Dec | Dev Procure