grant
Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study
Organization OREGON HEALTH & SCIENCE UNIVERSITYLocation PORTLAND, UNITED STATESPosted 15 Sept 2024Deadline 31 May 2028
NIHUS FederalResearch GrantFY2025Activities of Daily LivingActivities of everyday lifeAdolescentAdolescent YouthAdolescent and Young AdultAffectAfter CareAfter-TreatmentAftercareAgeAnemiaAngiohemophiliaBleedingBlood Coagulation DisordersBlood TestsCaringClinicClinical TrialsCoagulation DisorderCoagulopathyControl GroupsCorlutinaCorluviteCounselingCyclogestD-NorgestrelDataData SystemsDiagnosisDiagnosticDiagnostic testsDrugsEffectivenessEnrollmentEvidence based practiceExclusionFactor VIII-Related AntigenFamilyFe deficiencyFe elementFerritinGestagenic AgentsGestagensGestironGestoneGoalsHealthHealth StatusHematologic TestsHematological TestsHematology TestingHemorrhageHemostatic AgentsHemostaticsHeritabilityHormonalHospital AdmissionHospitalizationIT SystemsIncidenceInformation SystemsInformation Technology SystemsInterdisciplinary ResearchInterdisciplinary StudyIntrauterine Contraceptive DevicesIntrauterine DevicesInvestigationInvestigatorsIronKnowledgeLeftLevel of HealthLevonorgestrelLifeLipo-LutinLuteohormoneLutocyclinLutocylin MLutogylLutromoneMeasurementMeasuresMedicationMental HealthMental HygieneMethodsMultidisciplinary CollaborationMultidisciplinary ResearchNorethindrone acetateNorethisterone AcetateOralOutcomeOutcome AssessmentParticipantPatient Outcomes AssessmentsPatient Reported MeasuresPatient Reported OutcomesPatient Self-ReportPatientsPersonsPharmaceutical PreparationsPhysiologicPhysiologicalPopulationPragmatic clinical trialProgestagenic AgentsProgestasertProgestational AgentsProgestational CompoundsProgestational HormonesProgesterone AgentsProgestin TherapyProgestinsProgestogelProgestogensProgestolProgestonProlidonProlutonProspective StudiesProviderPsychological HealthQOLQOL improvementQuality of lifeQuestionnairesRecommendationRecordsReportingResearchResearch PersonnelResearchersResidualResidual stateRetrospective StudiesRistocetin CofactorRistocetin-Willebrand FactorSafetySchoolsScienceSelf-ReportSiteSpecialistStressSymptom BurdenSyngesteroneTest ResultTestingTherapeuticTherapeutic ProgestinTransfusionTreatment outcomeUtrogestanVascular HemophiliaVon willebrand factor deficiencyWillebrand diseaseWorkYouthYouth 10-21agesbleeding disorderblood lossclotting disordercompare treatmentdaily living functiondaily living functionalitydisease diagnosticdrug/agenteffective therapyeffective treatmentenrollexperiencefunctional abilityfunctional capacityhealth assessmenthealth levelhealth related quality of lifeimprovedimprovements in QOLimprovements in quality of lifeintra-uterine contraceptionintra-uterine contraceptive deviceintra-uterine deviceintra-uterine systemintrauterine contraceptionintrauterine systemiron deficiencyjuvenilejuvenile humanl-Norgestrelmembermultidisciplinarynew diagnosticsnext generation diagnosticsnovel diagnosticsphysical conditioningphysical healthpost treatmentpragmatic effectiveness trialpragmatic trialprimary outcomeprospectivequality of life improvementsatisfactionsecondary outcomesuccesstooltreatment comparisonvWFAgvon Willebrand Diseasevon Willebrand Factorvon Willebrand Factor Antigenvon Willebrand Proteinyouth age
Description preview
ABSTRACT
Heavy menstrual bleeding (HMB) is common among adolescents and young adults with a heritable bleeding
disorder (BD) and negatively impacts health-related quality of life and physical and mental health status.
Effective treatment options are available that decrease bleeding and improve quality of life, but were not
studied in those with…
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