grant

Health Equity Focused Clinical Decision Supports to Prevent Teen Substance Use in Pediatric Primary Care

Organization YALE UNIVERSITYLocation NEW HAVEN, UNITED STATESPosted 15 May 2025Deadline 30 Apr 2027
NIHUS FederalResearch GrantFY20250-11 years old12 year old12 years of ageAdolescentAdolescent YouthAdoptionAgeAlcohol Chemical ClassAlcoholsAwarenessBlackBlack raceCare GiversCaregiversCaringChildChild RearingChild YouthChildhoodChildren (0-21)CitiesClinicalCognitive DiscriminationCommunitiesCommunity prevention programsComplexConsolidated Framework for Implementation ResearchConsolidated Framework for Implementation ScienceConsolidated Framework for Implementing ChangeCounselingCountryDecrease disparityDedicationsDisciplineDiscriminationDisparitiesDisparityEffectivenessEmotionalEnrollmentEquityEventFamilyFederally Qualified Health CenterFundingFutureHealthHealth CareHealth InequityHealth InformaticsHealth PromotionHealth equity researchHospital AdmissionHospitalizationImprove AccessInequalities in HealthInequities in HealthInequityInfrastructureLatinoLinkLow incomeLower disparityMaintenanceNIDANational Institute of Drug AbuseNational Institute on Drug AbuseOutcomeParentingParenting behaviorParentsPatientsPersonsPhasePositionPositioning AttributePreventative interventionPreventionPrevention ResearchPrevention programPrimary CareProcessPublic HealthPublic Health InformaticsQualitative MethodsRE-AIMRandomizedReach, Effectiveness, Adoption, Implementation, and MaintenanceRecommendationResearchResearch ResourcesResearch in health equityResourcesRiskSalutogenesisScienceScientistServicesSystemTHC co-useTHC useTeenTeenagersTestingTetrahydrocannabinol co-useTetrahydrocannabinol useTimeVaccinationWell Child VisitsWell child checksWell child checkupsWell child examYouthYouth 10-21adolescent substance useage 12 yearsagedagescannabis usechild routine wellness visitschild wellness visitchildrearingclinical decision supportclinical practiceclinician factorsclinician-level factorscommunity engaged participatory researchcommunity engaged researchcommunity partnered researchcommunity partnershipcommunity-engaged studycommunity-partnered studyconsumer informaticsdesigndesigningdisparity reductionelderly patientenrollevidence baseexperiencefederal poverty levelhealth and care deliveryhealth care deliveryhealth delivery systemshealth equityhealth equity-focused researchhealth inequalitieshealth services deliveryimplementation frameworkimplementation research frameworkimplementation scienceimplementation science frameworkimplementation strategyimprovedintervention for preventionjuvenilejuvenile humankidslower income familiesmarijuana usemitigate disparitymultidisciplinarynovelolder patientopiate deathsopiate mortalityopioid deathsopioid mortalityopioid overdose deathopioid related deathparentparent monitoringparental monitoringpediatricpediatric preventive visitpediatric well visitphysician factorsphysician-level factorspre-adolescentpreadolescencepreteenpreventprevent substance usepreventingprevention interventionprevention servicepreventional intervention strategypreventive interventionprogramspromoting healthprovider factorsprovider-level factorsqualitative reasoningracismrandomisationrandomizationrandomly assignedreach, efficacy, adoption, implementation, and maintenancereduce disparityreduced substance usereduction in disparityreduction in substance useresearch on health equityresearch related to health equityresearch to attain health equityresponseroutine child health visitscreeningscreeningsskillssocial determinantssocial health determinantssociodeterminantstandard carestandard treatmentstrategies for implementationsubstance usesubstance use among adolescentssubstance use among youthsubstance use preventionsubstance use reductionsubstance usingsupport toolsteen yearsteenagetooltwelve year oldtwelve years of ageuptakeusabilityuser centered designyoungsteryouth ageyouth substance use
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Full Description

PROJECT SUMMARY
In the US, complex interactions between social determinants of health and underlying systems of racism and

discrimination collectively contribute to multiple health inequities associated with substance use. Upstream

prevention efforts can help reduce these inequities. NIDA-funded research has produced numerous evidence-

based substance use prevention interventions, including several that are family-focused. Family-focused

programs promote protective parenting skills––e.g., provision of warmth, parental monitoring, and positive

discipline––to reduce substance use risk in adolescents. Although effective, family-focused programs have

limited reach for low-income families due to multiple structural barriers. Integrating family-focused programs into

existing infrastructures that serve these families can help overcome barriers. Federally qualified health centers

(FQHCs)deliver low-barrier healthcare to30.5 million people (90% of whom live at or below 200% of the Federal

Poverty Level). They are ideally positioned to expandequitable access to family-focused prevention programs.

In

implementation strategy to

response to PAR-24-062,

Support Pre-Adolescents and families' linkage to substance use pRevention services

we propose one of the first studies to co-design (R61) and test (R33) a novel

inprimary Care (SPARC).Partnering with parents (i.e., caregivers), clinicians, FQHC leaders, and a non-profit

dedicated to strengthening FQHCs across CT, thestudy will occur in alarge FQHC that serves >18,000 low-

income children in New Haven, CT. The study brings together a diverse team of experts in adolescent substance

use prevention, implementation science, health equity research, and health informatics. SPARC

co-designed

12-year-old a locally delivered family-focused substance use prevention program,

Guiding Good Choices. Guiding Good Choices has demonstrated effectiveness in preventing adolescent

substance use by improving protective parenting skills. Guided by the Health Equity Implementation Framework,

Consolidated Framework for Implementation Research, and RE-AIM frameworks, during the R61 Planning

Phase, we aim to develop the SPARC implementation strategy with input from diverse stakeholders (R61 Aim

1) and evaluate its usability, acceptability, and feasibility in real-world clinical practice (R61 Aim 2). Upon

successful completion of R61 milestones, we will examine SPARC's impact on Guiding Good Choices adoption

and reach through a pragmatic RCT of clinicians (R33 Aim 1). We will also examine organizational, clinician

(R33 Aim 2), and caregiver-level (R33 Aim 3) factors that influence SPARC's adoption and reach. The

engagement of end-users, robust community partnerships, and experts across CT aligns with PAR-24-062's

emphasis on community-driven studies that engage community experts. Completing the proposed studies will

will include a

clinical decision support tool, and referral process to link caregivers of 9 –

patients in primary care to

clinical recommendation,

prepare us to scale evidence-based substance use prevention programs across FQHCs.

Grant Number: 1R61DA062103-01
NIH Institute/Center: NIH

Principal Investigator: Deepa Camenga

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