grant

HD2A RASC-Research and Evaluation Core

Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 30 Sept 2022Deadline 31 Aug 2027
NIHUS FederalResearch GrantFY2025AccelerationAddressAdoptionApplication ContextAreaAssess implementationComplexCore AssemblyDataData CollectionData ReportingDecision MakingDissemination and ImplementationEconomicsEvaluationEvaluation ReportsEvidence based interventionEvidence based practiceFutureGoalsHealth BenefitImplementation assessmentInsurance CoverageInsurance StatusInterventionInterviewInvestmentsKnowledgeMeasurementMeasuresMethodologyMethodsModelingMonitorMotivationNational Institutes of HealthPainPain ControlPain TherapyPain managementPainfulPersonsPhasePoliciesPrimary PreventionPublic HealthQualifyingR-Series Research ProjectsR01 MechanismR01 ProgramRecoveryReportingResearchResearch GrantsResearch MethodologyResearch MethodsResearch Project GrantsResearch ProjectsResearch ResourcesResourcesRoleScienceScientistStandardizationSubstance Use DisorderSurvey InstrumentSurveysSystemTestingTranslational ResearchTranslational ScienceUnited States National Institutes of HealthWorkaddictionaddictive disorderbarriers to implementationcareercontextual factorsdata harmonizationdata infrastructuredata representationdata representationsdesigndesigningdiscovery miningeconomicevaluate implementationevaluation of implementationevaluation/testingexperienceformative assessmentformative evaluationharmonized dataimplementation barriersimplementation challengesimplementation evaluationimplementation facilitationimplementation outcomesimplementation researchimplementation scienceimplementation strategyinnovateinnovationinnovativeinsightliterature miningliterature searchingmedication for opioid use disordermodel-based simulationmodels and simulationmultidisciplinaryoverdose deathoverdose fatalitiespain interventionpain treatmentprogramsresearch and methodsscale upscreeningscreeningssocial rolestrategies for implementationsubstance usesubstance use and disordersubstance usingtext miningtext searchingtooltranslation researchtranslational investigation
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Full Description

RESEARCH AND EVALUATION CORE: PROJECT SUMMARY/ABSTRACT
Although effective primary prevention, treatment, and recovery-oriented support interventions for substance use disorders and pain exist, they are not widely available. Crosscutting implementation science (IS) methods are required to select and deliver effective and efficient implementation strategies under variable contexts. The Research Adoption Support Center’s Research and Evaluation (R&E) Core, in concert with the Administrative, Substance Use Disorder Implementation Support (SUD-IS) and Pain Implementation Support (Pain-IS) cores, utilizes an integrated, multidisciplinary, iterative approach to provide rapid assessment, expert technical assistance, and advance the long-term adoption and sustainment of evidence-based interventions. The overarching goal of the R&E Core is to elevate the capability for translational long-term impact of the HD2A Innovation/Acceleration Projects. We achieve this via standardized baseline information and on-demand support for data, analytic, and research translation needs, all toward leveraging sustainable change through science-based financing and policies. We will provide state-of-the-art methodological support in IS measurement, frameworks, modeling, and testing/evaluation, guided by R&E Core experts who have conducted extensive work across the four HHS pillars. Aligned with other RASC cores, we are guided by 3 dynamic phases: 1) ASSESS Innovation/Acceleration Projects’ baseline IS capacity via 3 methods; 2) ASSIST the Innovation/Acceleration Projects in increasing IS capability, while supporting harmonized data collection and reporting across projects; and, 3) ADVANCE Innovation/Acceleration Projects’ potential for sustainment and scale-up, and serve as the IS research methodology resource to the HD2A Modeling and Economic Resource Center (MERC) and Data Infrastructure Support Center (DISC). A key function of the R&E core is the formative evaluation, a phased evaluation that will incorporate lessons learned within and across HD2A grantees, with formative evaluation reports (Years 1, 3) focused on providing insight to support timely decision- making and course corrections by grantees and NIH, and a final report (Year 5) focused on informing future initiatives of this kind. We also will conduct 5 Rapid Turnaround Research Projects designed to produce knowledge to address persistent or emerging barriers to implementation or sustainment identified by HD2A grantees. The Year 1 project will focus on the role of insurance coverage and other financing and reimbursement barriers to the widespread adoption of medications for opioid use disorder (MOUD). Within and beyond the HD2A program, we boldly seek to contribute knowledge and methods to the addiction and pain intervention fields with the ultimate goal of transformational public health benefit.

Grant Number: 5U2CDA057717-04
NIH Institute/Center: NIH

Principal Investigator: C. BROWN

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