Harnessing the Power of Enzymes in Sustainable Organic Synthesis
Description preview
Cycloadditions of conjugated dienes and dienophiles, known as the Diels-Alder reaction, are of significant synthetic value due to the formation of a substituted cyclohexene along with up to four new stereocenters. Identification of enzymes which catalyse this reaction (Diels-Alderases) would enable highly chemo-, regio- and enantiospecific,…
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